Saboo Keyur, Gemnani Rinkle R, Manuja Nishtha, Kumar Sunil, Acharya Sourya
Department of Medicine, Jawaharlal Nehru Medical College, Wardha, IND.
Department of Internal Medicine, Jawaharlal Nehru Medical College, Wardha, IND.
Cureus. 2023 Jun 13;15(6):e40389. doi: 10.7759/cureus.40389. eCollection 2023 Jun.
We present a case of neonatal goiter caused by exposure to propylthiouracil (PTU) during pregnancy in this case report. The mother was treated with PTU while pregnant and had a history of Graves' illness. The baby had a neck tumor and was having breathing problems when they were first seen. A big thyroid gland was detected by a neck CT scan. This instance serves as a reminder of the significance of managing maternal thyroid problems appropriately during pregnancy as well as the requirement for careful thyroid function monitoring in newborns exposed to PTU. Given the possible hazards to the growing baby, it also calls into question whether PTU is an effective first-line treatment for maternal Graves' illness during pregnancy. This case report highlights the importance of shared decision-making with patients (by discussing different treatment options and their side effects).
在本病例报告中，我们呈现了一例因孕期接触丙硫氧嘧啶（PTU）导致的新生儿甲状腺肿病例。母亲在孕期接受了PTU治疗，并有格雷夫斯病病史。婴儿首次就诊时颈部有肿物且存在呼吸问题。颈部CT扫描发现一个肿大的甲状腺。该病例提醒人们，孕期妥善管理母亲的甲状腺问题具有重要意义，同时也凸显了对接触PTU的新生儿进行甲状腺功能密切监测的必要性。鉴于对发育中胎儿可能存在的危害，这也引发了关于PTU是否为孕期母亲格雷夫斯病有效一线治疗药物的质疑。本病例报告强调了与患者共同决策（通过讨论不同治疗方案及其副作用）的重要性。
