Kettleman William S, Jaffe Michael H, Wills Robert W, Dietz Sara J, Elder Steve H
Department of Clinical Sciences, College of Veterinary Medicine, Mississippi State University, Starkville, MS, United States.
Department of Comparative Biomedical Sciences, College of Veterinary Medicine, Mississippi State University, Starkville, MS, United States.
Front Vet Sci. 2023 Jun 29;10:1207563. doi: 10.3389/fvets.2023.1207563. eCollection 2023.
The objective of this study was to investigate the effect of a novel screw type on stiffness and failure characteristics of a tibial plateau leveling osteotomy (TPLO) construct under cyclic loading conditions. The authors hypothesized that bone-screw-fasteners (BSF) would result in superior biomechanical stability compared with locking buttress screws (LBS).
Twelve pairs of canine cadaveric pelvic limbs were included in this biomechanical study. A TPLO was performed using a 3.5mm locking TPLO plate and stabilized using either LBS or BSF. Cyclic loading was performed for 30,000 cycles at 4Hz with a peak-load of 1000N (50N valley). The cyclic test was then continued by stepwise incremental increase of peak-load at a rate of 75N per 500 cycles until failure.
Cycles to failure for LBS (44,260 ± 5,770) and BSF (41,540 ± 7,686) were not significantly different ( = 0.36). Maximum force for LBS (3,134 ± 797N) and BSF (2,940 ± 831N) was not significantly different either ( = 0.58). Dynamic stiffness for LBS (1,778 ± 932 N/mm) and BSF (1,574 ± 677 N/mm) was not significantly different ( = 0.58).
Stabilization of the TPLO with BSF provided similar biomechanical stability under cyclic axial loading conditions as the LBS. BSF may be an acceptable alternative to traditional locking screws for TPLO.
本研究的目的是在循环加载条件下，研究一种新型螺钉类型对胫骨平台平整截骨术（TPLO）结构的刚度和失效特性的影响。作者假设，与锁定支撑螺钉（LBS）相比，骨螺钉固定件（BSF）将产生更好的生物力学稳定性。
本生物力学研究纳入了12对犬尸体骨盆肢体。使用3.5毫米锁定TPLO钢板进行TPLO，并使用LBS或BSF进行固定。以4Hz的频率进行30000次循环加载，峰值载荷为1000N（谷值为50N）。然后以每500次循环增加75N的速率逐步增加峰值载荷，继续进行循环测试，直至失效。
LBS（44260±5770）和BSF（41540±7686）的失效循环次数无显著差异（P = 0.36）。LBS（3134±797N）和BSF（2940±831N）的最大力也无显著差异（P = 0.58）。LBS（1778±932N/mm）和BSF（1574±677N/mm）的动态刚度无显著差异（P = 0.58）。
在循环轴向加载条件下，用BSF固定TPLO提供了与LBS相似的生物力学稳定性。对于TPLO，BSF可能是传统锁定螺钉的可接受替代方案。
