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猫胃扩张引起的食管下括约肌反射性兴奋和抑制

Reflex excitation and inhibition of the lower oesophageal sphincter induced by gastric distension in the cat.

作者信息

Niel J P

出版信息

J Auton Nerv Syst. 1986 Jul;16(3):205-9. doi: 10.1016/0165-1838(86)90026-3.

DOI:10.1016/0165-1838(86)90026-3
PMID:3745776
Abstract

Reflex responses of the lower oesophageal sphincter (l.o.s.) to distension of the stomach were studied by electromyographic and manometric techniques. Distension of the fundus and gastric antrum by inflation of a balloon elicited two types of reflex response of the l.o.s. Thus, whereas excitatory responses were recorded following slight distensions, larger distensions resulted in inhibitory responses. Splanchnic fibres and sympathetic fibres originating from the stellate ganglion, as well as vagal fibres served as the efferent pathways for the excitatory reflex response. The efferent pathways for the inhibitory response involved only vagal fibres.

摘要

采用肌电图和测压技术研究了胃扩张时下食管括约肌(l.o.s.)的反射反应。通过向气囊充气使胃底和胃窦扩张,引发了下食管括约肌的两种反射反应。因此,轻微扩张后记录到兴奋性反应,而较大扩张则导致抑制性反应。发自星状神经节的内脏纤维和交感纤维以及迷走神经纤维作为兴奋性反射反应的传出通路。抑制性反应的传出通路仅涉及迷走神经纤维。

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