青少年焦虑症跨诊断治疗的文化适应性统一方案（UP-A）：一项随机等待名单对照试验。
A culturally adapted unified protocol for transdiagnostic treatment of anxiety disorders in adolescents (UP-A): a randomized waitlist-controlled trial.
作者信息
Zemestani Mehdi, Ezzati Saman, Nasiri Farzad, Gallagher Matthew W, Barlow David H, Kendall Philip C
机构信息
Department of Psychology, University of Kurdistan, Sanandaj, Iran.
Department of Psychology, University of Houston, Houston, TX, USA.
出版信息
Psychol Med. 2024 Jan;54(2):385-398. doi: 10.1017/S0033291723001903. Epub 2023 Jul 17.
BACKGROUND
Anxiety disorders are highly prevalent and debilitating conditions that show high comorbidity rates in adolescence. The present article illustrates how Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Adolescents (UP-A) was adapted for Iranian adolescents with anxiety disorders.
METHODS
A total of 54 adolescents with comorbid anxiety disorders participated in a randomized, waitlist-controlled trial of group weekly sessions of either UP-A or waitlist control (WLC). Primary and process of change outcomes were assessed at baseline, posttreatment, and 1-month follow-up.
RESULTS
Significant changes were observed over time on major DSM-5 anxiety disorder symptoms ( = 117.09, < 0.001), phobia type symptoms ( = 100.67, < 0.001), and overall anxiety symptoms ( = 196.29, < 0.001), as well as on emotion regulation strategies of reappraisal ( = 17.03, < 0.001), and suppression ( = 21.13, < 0.001), as well as on intolerance of uncertainty dimensions including prospective ( = 74.49, < 0.001), inhibitory ( = 45.94, < 0.001), and total intolerance of uncertainty ( = 84.42, < 0.001), in favor of UP-A over WLC.
CONCLUSION
Overall, results provide a cultural application of the UP-A and support the protocol as useful for improving anxiety disorders as well as modifying of emotion regulation strategies and intolerance of uncertainty dimensions in Iranian adolescents. Future directions and study limitations are discussed.
背景
焦虑症在青少年中极为普遍且使人衰弱，在青少年中具有很高的共病率。本文阐述了青少年情绪障碍跨诊断治疗统一方案（UP - A）如何适用于患有焦虑症的伊朗青少年。
方法
共有54名患有共病焦虑症的青少年参与了一项随机、等待列表对照试验，该试验为每周一次的小组治疗，治疗方式为UP - A或等待列表对照（WLC）。在基线、治疗后和1个月随访时评估主要变化结果和变化过程。
结果
随着时间推移，在主要的《精神疾病诊断与统计手册》第五版（DSM - 5）焦虑症症状（ = 117.09， < 0.001）、恐惧症类型症状（ = 100.67， < 0.001）、总体焦虑症状（ = 196.29， < 0.001）方面，以及在重新评估（ = 17.03， < 0.001）和抑制（ = 21.13， < 0.001）的情绪调节策略方面，还有在不确定性不耐受维度，包括预期性（ = 74.49， < 0.001）、抑制性（ = 45.94， < 0.001）和总体不确定性不耐受（ = 84.42， < 0.001）方面，均观察到显著变化，表明UP - A组优于等待列表对照组（WLC）。
结论
总体而言，研究结果提供了UP - A的文化应用实例，并支持该方案对改善伊朗青少年焦虑症、调节情绪调节策略以及降低不确定性不耐受维度方面是有用的。文中还讨论了未来的研究方向和研究局限性。
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