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[重症监护中的睡眠:一个关键但鲜为人知的问题]

[Sleep in intensive care: a crucial but little-known issue].

作者信息

Drouot Xavier

机构信息

Inserm, CIC 1402, CHU de Poitiers, Poitiers, France ; CHU de Poitiers, service de neurophysiologie clinique, Poitiers, France ; Inserm U-1084, Laboratoire de neurosciences expérimentales et cliniques, Neurobiology and Neuroplasticity and Neuro-development Group, Poitiers, France ; faculté de médecine et pharmacie, université de Poitiers.

出版信息

Rev Prat. 2023 Jun;73(6):669-675.

Abstract

A CRUCIAL BUT LITTLE-KNOWN ISSUE. Polysomnography is the best tool to study sleep in intensive care unit (ICU), but this recording is complex to perform in such environment. Sleep alterations in ICU patients are specific and include electroencephalographic abnormalities during sleep and wake, rendering sleep scoring more complicated. Severe deficit in deep sleep, rapid eye movement sleep and an important sleep fragmentation are reported by most studies. Sleep cycles are disorganized with many sleep episodes during daytime. Sleep disruptions result from light levels, noisy environment, and 24-hours nurses care. Assisted ventilation, sedation, loss of circadian rhythms also contribute to these disruptions. Biological and neurobehavioral consequences of sleep alterations lengthen weaning from mechanical ventilation and have some deleterious impacts on morbidity and mortality. Procedures to promote sleep have been attempted, with limited results to date. However, recent innovation might help to monitor sleep and help patients to achieve some restorative sleep.

摘要

一个关键但鲜为人知的问题。多导睡眠图是研究重症监护病房(ICU)睡眠的最佳工具,但在这种环境下进行记录很复杂。ICU患者的睡眠改变具有特殊性,包括睡眠和清醒时的脑电图异常,这使得睡眠评分更加复杂。大多数研究报告称,深度睡眠、快速眼动睡眠严重不足,且睡眠碎片化严重。睡眠周期紊乱,白天有许多睡眠片段。睡眠中断是由光照水平、嘈杂环境和24小时护士护理导致的。辅助通气、镇静、昼夜节律丧失也会导致这些干扰。睡眠改变的生物学和神经行为后果会延长机械通气撤机时间,并对发病率和死亡率产生一些有害影响。人们已经尝试了促进睡眠的方法,迄今为止效果有限。然而,最近的创新可能有助于监测睡眠,并帮助患者获得一些恢复性睡眠。

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