Korompeli Anna, Muurlink Olav, Kavrochorianou Nadia, Katsoulas Theodoros, Fildissis George, Baltopoulos George
National and Kapodistrian University of Athens, School of Health Sciences, ICU Research Unit at "Agioi Anargyroi" General Hospital, Greece.
Central Queensland University, Brisbane, Griffith Institute of Educational Research, Brisbane, Australia.
J Crit Care. 2017 Apr;38:269-277. doi: 10.1016/j.jcrc.2016.12.006. Epub 2016 Dec 13.
Intensive care unit patients typically exhibit pathologic wakefulness, poor quality of daytime sleep, nocturnal sleep fragmentation, and sleep patterns that feature the absence of slow wave sleep and rapid eye movement. This article offers a review of the existing literature examining circadian desynchronization in critically ill patients, highlighting contributing factors identified by scholars, and circadian abnormalities observed in these patients. It discusses potential implications for clinical practice and suggests avenues of future research. Elucidating the role of circadian rhythms in the management of critical illness can guide future chronotherapeutic approaches and optimize patient outcomes.
重症监护病房的患者通常表现出病理性觉醒、白天睡眠质量差、夜间睡眠碎片化以及缺乏慢波睡眠和快速眼动的睡眠模式。本文综述了现有关于危重症患者昼夜节律失调的文献，强调了学者们确定的促成因素以及在这些患者中观察到的昼夜节律异常。它讨论了对临床实践的潜在影响，并提出了未来的研究方向。阐明昼夜节律在危重症管理中的作用可以指导未来的时间治疗方法并优化患者预后。
