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童年创伤经历对中国男性甲基苯丙胺使用障碍患者反刍思维与药物渴求的影响

Association between rumination and drug craving in Chinese male methamphetamine use disorder patients with childhood trauma.

机构信息

CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China; Department of Psychology, University of Chinese Academy of Sciences, Beijing, China.

CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China; Department of Psychology, University of Chinese Academy of Sciences, Beijing, China.

出版信息

Child Abuse Negl. 2023 Oct;144:106357. doi: 10.1016/j.chiabu.2023.106357. Epub 2023 Jul 15.

Abstract

BACKGROUND

In China, males make up the majority of methamphetamine (MA) dependent individuals and the majority of treatment seekers. Childhood trauma (CT) and rumination are associated with an increased risk of MA use. However, the association between CT, rumination, and drug craving remains largely unknown.

OBJECTIVE

The present study aims to explore the association between rumination and drug craving in methamphetamine use disorder (MAUD) patients with CT.

PARTICIPANTS AND SETTING

This study recruited 404 male participants with MAUD from a male drug rehabilitation center in Southwest China.

METHODS

Patients with CT were identified by the short form of Childhood Trauma Questionnaire (CTQ-SF). Rumination and drug craving were assessed by the Ruminative Responses Scale (RRS) and the Obsessive Compulsive Drug Use Scale (OCDUS), respectively.

RESULTS

188 patients (46.5 %) experienced CT. Patients who had experienced CT showed significantly higher RRS symptom rumination score and OCDUS total score than those who had not. In patients with CT, RRS total and all subscale scores were positively associated with OCDUS interference of drug. Furthermore, the RRS brooding (β = 0.34, p < 0.001) and total scores (β = 0.38, p < 0.001) were determined to be separate contributors to the OCDUS total score in patients with CT.

CONCLUSIONS

Our study suggests that CT is common in male MAUD patients, and those who have suffered CT may exhibit higher levels of rumination and drug craving. Moreover, CT may play an influential role in the association between rumination and drug craving in patients with MAUD.

摘要

背景

在中国,男性在甲基苯丙胺(MA)依赖者和大多数寻求治疗者中占多数。童年创伤(CT)和反刍与 MA 使用风险增加有关。然而,CT、反刍和药物渴求之间的关联在很大程度上仍不清楚。

目的

本研究旨在探讨 CT 与 MA 药物使用障碍(MAUD)患者反刍与药物渴求之间的关系。

参与者和设置

本研究招募了来自中国西南地区一家男性戒毒中心的 404 名 MAUD 男性患者。

方法

采用儿童期创伤问卷(CTQ-SF)短式对 CT 进行评估。采用反刍反应量表(RRS)和强迫性药物使用量表(OCDUS)分别评估反刍和药物渴求。

结果

188 例(46.5%)患者经历过 CT。有 CT 经历的患者表现出明显更高的 RRS 症状反刍评分和 OCDUS 总分。在 CT 患者中,RRS 总分和所有子量表评分均与 OCDUS 药物干扰呈正相关。此外,RRS 沉思(β=0.34,p<0.001)和总分(β=0.38,p<0.001)被确定为 CT 患者 OCDUS 总分的独立贡献者。

结论

我们的研究表明,CT 在男性 MAUD 患者中很常见,经历过 CT 的患者可能表现出更高水平的反刍和药物渴求。此外,CT 可能在 MAUD 患者反刍和药物渴求之间的关系中起重要作用。

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