Mao Yinxue, Li Deyang, Wang Dongmei, Tian Yang, Chen Jiajing, Jia Lianglun, Wang Xiaotao, Zhang Xiang-Yang
CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China.
Department of Psychology, University of Chinese Academy of Sciences, 16 Lincui Road, Chaoyang District, Beijing, 100101, China.
Subst Abuse Treat Prev Policy. 2025 Mar 26;20(1):14. doi: 10.1186/s13011-025-00643-z.
Rumination is an essential trans-diagnostic process associated with substance use disorders (SUDs) in psychopathology. In China, methamphetamine and heroin have become major illegal drugs, but the role of rumination in their use remains unclear. The objective of this study was to investigate the relationship between rumination subtypes and drug craving in patients with methamphetamine use disorder (MAUD) and 81 patients with heroin use disorder (HUD).
A total of 489 participants, including 408 patients with MAUD and 81 patients with HUD, were recruited from a rehabilitation center. Participants were screened for inclusion criteria, and the Obsessive Compulsive Drug Use Scale (OCDUS) was used to assess drug craving. Rumination was assessed using the Ruminative Responses Scale (RRS), categorized into three dimensions: symptom rumination, brooding, and reflective pondering. Correlational and multiple regression analyses were conducted to examine associations between rumination and craving.
Compared to patients with MAUD, patients with HUD had significantly higher RRS and OCDUS total score (42.51 vs 39.71 and 25.99 vs 20.95, both p < 0.01). In patients with MAUD, the OCDUS total score was positively correlated with the total score (r = 0.298, p < 0.01) and all subscale scores of the RRS (for reflective pondering, r = 0.180; for brooding, r = 0.230; for symptom rumination, r = 0.325; all p < 0.01). However, in patients with HUD, only symptom rumination was positively associated with the OCDUS total score (r = 0.247, p < 0.05). Multiple regression showed symptom rumination was independently associated with OCDUS total score in both groups (for patients with MAUD, β = 0.324, p < 0.001; for patients with HUD, β = 0.252, p < 0.05).
Our findings suggest that rumination shows different effects on craving in male patients with MAUD and HUD. Moreover, symptom rumination may have a significant influence on the connection between rumination and craving in individuals with MAUD and HUD.
反刍思维是心理病理学中与物质使用障碍(SUDs)相关的一个重要的跨诊断过程。在中国,甲基苯丙胺和海洛因已成为主要的非法毒品,但反刍思维在其使用中的作用仍不清楚。本研究的目的是调查反刍思维亚型与甲基苯丙胺使用障碍(MAUD)患者和81例海洛因使用障碍(HUD)患者的药物渴望之间的关系。
从一家康复中心招募了总共489名参与者,包括408例MAUD患者和81例HUD患者。对参与者进行纳入标准筛查,并使用强迫性药物使用量表(OCDUS)评估药物渴望。使用反刍反应量表(RRS)评估反刍思维,分为三个维度:症状反刍、沉思和反思性思考。进行相关分析和多元回归分析以检验反刍思维与渴望之间的关联。
与MAUD患者相比,HUD患者的RRS和OCDUS总分显著更高(分别为42.51对39.71以及25.99对20.95,均p<0.01)。在MAUD患者中,OCDUS总分与RRS总分(r=0.298,p<0.01)以及RRS的所有子量表得分呈正相关(反思性思考方面,r=0.180;沉思方面,r=0.230;症状反刍方面,r=0.325;均p<0.01)。然而,在HUD患者中,仅症状反刍与OCDUS总分呈正相关(r=0.247,p<0.05)。多元回归显示,症状反刍在两组中均与OCDUS总分独立相关(MAUD患者中,β=0.324,p<0.001;HUD患者中,β=0.252,p<0.05)。
我们的研究结果表明,反刍思维对MAUD和HUD男性患者的渴望有不同影响。此外,症状反刍可能对MAUD和HUD个体中反刍思维与渴望之间的联系有显著影响。