Wang Tong, Gao Botao, Yu Zhou, Song Baoqiang
Department of Plastic Surgery, the First Affiliated Hospital of Air Force Medical University, Xi'an Shaanxi, 710032, P. R. China.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2023 Jul 15;37(7):901-906. doi: 10.7507/1002-1892.202302077.
To summarize the research progress of surgical technique and immunosuppressive regimen of abdominal wall vascularized composite allograft transplantation in animals and clinical practice.
The literature on abdominal wall transplantation at home and abroad in recent years was extensively reviewed and analyzed.
This review includes animal and clinical studies. In animal studies, partial or total full-thickness abdominal wall transplantation models have been successfully established by researchers. Also, the use of thoracolumbar nerves has been described as an important method for functional reconstruction and prevention of long-term muscle atrophy in allogeneic abdominal wall transplantation. In clinical studies, researchers have utilized four revascularization techniques to perform abdominal wall transplantation, which has a high survival rate and a low incidence of complications.
Abdominal wall allotransplantation is a critical reconstructive option for the difficulty closure of complex abdominal wall defects. Realizing the recanalization of the nerve in transplanted abdominal wall to the recipient is very important for the functional recovery of the allograft. The developments of similar research are beneficial for the progress of abdominal wall allotransplantation.
总结腹壁带血管复合组织同种异体移植在动物实验及临床应用中的手术技术和免疫抑制方案的研究进展。
广泛查阅并分析近年来国内外有关腹壁移植的文献。
本综述涵盖动物及临床研究。在动物研究中，研究人员已成功建立部分或全层腹壁移植模型。此外，胸腰段神经的应用被描述为同种异体腹壁移植功能重建及预防长期肌肉萎缩的重要方法。在临床研究中，研究人员采用了四种血管再通技术进行腹壁移植，其具有较高的成活率和较低的并发症发生率。
腹壁同种异体移植是复杂腹壁缺损难以闭合时的关键重建选择。实现移植腹壁神经与受者神经再通对同种异体移植物的功能恢复非常重要。类似研究的开展有利于腹壁同种异体移植的进步。
