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前庭神经核在疱疹性中耳炎或前庭神经炎引起的急性眩晕患者中的作用。

Vestibular Nucleus Involvement in Patients With Acute Vertigo Due to Herpes Zoster Oticus or Vestibular Neuritis.

机构信息

From the Department of Neurology (D.A.Y., T.I.), and Department of Neuroradiology (M.S.P.A.), Dr. Cesar Milstein Hospital, Buenos Aires, Argentina; Department of Neurology (M.C.), Feinberg School of Medicine, Northwestern University, Chicago; and Department of Neurology (M.C.), University of Chicago, IL.

出版信息

Neurology. 2023 Oct 3;101(14):e1461-e1465. doi: 10.1212/WNL.0000000000207549. Epub 2023 Jul 17.

DOI:10.1212/WNL.0000000000207549
PMID:37460229
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10573148/
Abstract

OBJECTIVES

Herpes zoster oticus (HZO) typically provokes vestibular symptoms and is traditionally viewed as a cranial nerve equivalent of shingles, but in contrast to vestibular neuritis (VN), it is unclear whether the pathology of HZO is limited to the vestibular nerve (neuritis) or can also involve the brainstem (nucleitis).

METHODS

We retrospectively compared brain MRIs of patients with HZO with those of patients with VN to study radiologic changes in the brainstem.

RESULTS

Five of 10 patients with HZO showed signal abnormalities in the vestibular nuclei, which lie in multiple vascular territories, whereas no patients with VN exhibited such findings.

DISCUSSION

HZO may at least in part reflect vestibular nucleitis, as opposed to a pure neuritis.

摘要

目的

耳带状疱疹(HZO)通常会引起前庭症状,传统上被视为带状疱疹的颅神经等效物,但与前庭神经炎(VN)不同的是,HZO 的病理是否仅限于前庭神经(神经炎),还是也可累及脑干(核炎)尚不清楚。

方法

我们回顾性比较了 HZO 患者和 VN 患者的脑部 MRI,以研究脑干的放射学变化。

结果

10 例 HZO 患者中有 5 例前庭核出现信号异常,这些核位于多个血管区域,而 VN 患者则无此发现。

讨论

HZO 至少部分反映了前庭核炎,而不是单纯的神经炎。

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本文引用的文献

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Brainstem Infarction and Vertebral Artery Vasculopathy After Ramsay Hunt Syndrome.拉姆齐·亨特综合征后的脑干梗死与椎动脉血管病变
Neurology. 2022 May 24;98(21):890-891. doi: 10.1212/WNL.0000000000200522. Epub 2022 Mar 29.
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A Topographic Atlas of the Human Brainstem in the Ponto-Mesencephalic Junction Plane.脑桥中脑交界平面的人脑干地形图集。
Front Neuroanat. 2021 Aug 13;15:627656. doi: 10.3389/fnana.2021.627656. eCollection 2021.
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The spectrum of acute vestibular neuropathy through modern vestibular testing: A descriptive analysis.通过现代前庭测试对急性前庭神经病变的频谱分析:描述性分析
Clin Neurophysiol Pract. 2021 Apr 14;6:137-145. doi: 10.1016/j.cnp.2021.02.008. eCollection 2021.
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Vestibular and cochlear nerve enhancement on MRI and its correlation with vestibulocochlear functional deficits in patients with Ramsay Hunt syndrome.磁共振成像中的前庭耳蜗神经增强及其与 Ramsay Hunt 综合征患者前庭耳蜗功能缺陷的相关性。
Auris Nasus Larynx. 2021 Jun;48(3):347-352. doi: 10.1016/j.anl.2020.08.027. Epub 2020 Sep 11.
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Brainstem and Cerebellar Involvement in Ramsay Hunt Syndrome.拉姆齐·亨特综合征中的脑干和小脑受累情况
Case Rep Otolaryngol. 2019 Dec 12;2019:7605056. doi: 10.1155/2019/7605056. eCollection 2019.
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Ramsay Hunt syndrome associated with solitary nucleus, spinal trigeminal nucleus and tract, and vestibular nucleus involvement on sequential magnetic resonance imaging.磁共振成像连续序列显示 Ramsay Hunt 综合征累及单一神经核、脊束核和脊束、前庭神经核。
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Vestibular Restoration and Adaptation in Vestibular Neuritis and Ramsay Hunt Syndrome With Vertigo.前庭神经炎和伴有眩晕的拉姆齐·亨特综合征中的前庭恢复与适应
Otol Neurotol. 2017 Aug;38(7):e203-e208. doi: 10.1097/MAO.0000000000001468.
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Varicella zoster virus infection: clinical features, molecular pathogenesis of disease, and latency.水痘带状疱疹病毒感染:临床特征、疾病的分子发病机制及潜伏状态
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