Panico Matteo, Chande Ruchi D, Lindsey Derek P, Mesiwala Ali, Polly David W, Villa Tomaso, Yerby Scott A, Brayda-Bruno Marco, Galbusera Fabio
IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
Department of Chemistry, Materials and Chemical Engineering "Giulio Natta", Politecnico di Milano, Milan, Italy.
Int J Spine Surg. 2023 Aug;17(4):598-606. doi: 10.14444/8481. Epub 2023 Jul 17.
Sacropelvic fixation is frequently combined with thoracolumbar instrumentation for correcting spinal deformities. This study aimed to characterize sacropelvic fixation techniques using novel porous fusion/fixation implants (PFFI).
Three T10-pelvis finite element models were created: (1) pedicle screws and rods in T10-S1, PFFI bilaterally in S2 alar-iliac (S2AI) trajectory; (2) fixation in T10-S1, PFFI bilaterally in S2AI trajectory, triangular implants bilaterally above the PFFI in a sacro-alar-iliac trajectory (PFFI-IFSAI); and (3) fixation in T10-S1, PFFI bilaterally in S2AI trajectory, PFFI in sacro-alar-iliac trajectory stacked cephalad to those in S2AI position (2-PFFI). Models were loaded with pure moments of 7.5 Nm in flexion-extension, lateral bending, and axial rotation. Outputs were compared against 2 baseline models: (1) pedicle screws and rods in T10-S1 (PED), and (2) pedicle screws and rods in T10-S1, and S2AI screws.
PFFI and S2AI resulted in similar L5-S1 motion; adding another PFFI per side (2-PFFI) further reduced this motion. Sacroiliac joint (SIJ) motion was also similar between PFFI and S2AI; PFFI-IFSAI and 2-PFFI demonstrated a further reduction in SIJ motion. Additionally, PFFI reduced max stresses on S1 pedicle screws and on implants in the S2AI position.
The study shows that supplementing a long construct with PFFI increases the stability of the L5-S1 and SIJ and reduces stresses on the S1 pedicle screws and implants in the S2AI position.
The findings suggest a reduced risk of pseudarthrosis at L5-S1 and screw breakage. Clinical studies may be performed to demonstrate applicability to patient outcomes.
Not applicable (basic science study).
骶骨盆固定术常与胸腰椎内固定术联合用于矫正脊柱畸形。本研究旨在使用新型多孔融合/固定植入物(PFFI)来描述骶骨盆固定技术。
创建了三个T10 - 骨盆有限元模型:(1)T10 - S1使用椎弓根螺钉和棒,双侧S2翼状髂骨(S2AI)轨迹植入PFFI;(2)T10 - S1固定,双侧S2AI轨迹植入PFFI,双侧在骶翼状髂骨轨迹中PFFI上方植入三角形植入物(PFFI - IFSAI);(3)T10 - S1固定,双侧S2AI轨迹植入PFFI,骶翼状髂骨轨迹中的PFFI堆叠在S2AI位置的PFFI上方(2 - PFFI)。模型在屈伸、侧方弯曲和轴向旋转时加载7.5 Nm的纯力矩。将输出结果与两个基线模型进行比较:(1)T10 - S1使用椎弓根螺钉和棒(PED),以及(2)T10 - S1使用椎弓根螺钉和棒以及S2AI螺钉。
PFFI和S2AI导致L5 - S1运动相似;每侧再添加一个PFFI(2 - PFFI)进一步减少了这种运动。骶髂关节(SIJ)运动在PFFI和S2AI之间也相似;PFFI - IFSAI和2 - PFFI显示SIJ运动进一步减少。此外,PFFI降低了S1椎弓根螺钉和S2AI位置植入物上的最大应力。
研究表明,用PFFI补充长节段固定可增加L5 - S1和SIJ的稳定性,并降低S1椎弓根螺钉和S2AI位置植入物上的应力。
研究结果提示L5 - S1假关节形成和螺钉断裂风险降低。可进行临床研究以证明其对患者预后的适用性。
不适用(基础科学研究)。