基于试点音调的心脏触发全面心血管磁共振检查的双中心验证

Two-center validation of Pilot Tone Based Cardiac Triggering of a Comprehensive Cardiovascular Magnetic Resonance Examination.

作者信息

Pan Yue, Varghese Juliet, Tong Matthew S, Yildiz Vedat O, Azzu Alessia, Gatehouse Peter, Wage Rick, Nielles-Vallespin Sonia, Pennell Dudley, Jin Ning, Bacher Mario, Hayes Carmel, Speier Peter, Simonetti Orlando P

机构信息

The Ohio State University.

The Ohio State University Wexner Medical Center.

出版信息

Res Sq. 2023 Jul 3:rs.3.rs-3121723. doi: 10.21203/rs.3.rs-3121723/v1.

Abstract

BACKGROUND

The electrocardiogram (ECG) signal is prone to distortions from gradient and radiofrequency interference and the magnetohydrodynamic effect during cardiovascular magnetic resonance imaging (CMR). Although Pilot Tone Cardiac (PTC) triggering has the potential to overcome these limitations, effectiveness across various CMR techniques has yet to be established.

PURPOSE

To evaluate the performance of PTC triggering in a comprehensive CMR exam.

METHODS

Fifteen volunteers and twenty patients were recruited at two centers. ECG triggered images were collected for comparison in a subset of sequences. The PTC trigger accuracy was evaluated against ECG in cine acquisitions. Two experienced readers scored image quality in PTC-triggered cine, late gadolinium enhancement (LGE), and T1- and T2-weighted dark-blood turbo spin echo (DB-TSE) images. Quantitative cardiac function, flow, and parametric mapping values obtained using PTC and ECG triggered sequences were compared.

RESULTS

Breath-held segmented cine used for trigger timing analysis was collected in 15 volunteers and 14 patients. PTC calibration failed in three volunteers and one patient; ECG trigger recording failed in one patient. Out of 1987 total heartbeats, three mismatched trigger PTC-ECG pairs were found. Image quality scores showed no significant difference between PTC and ECG triggering. There was no significant difference found in quantitative measurements in volunteers. In patients, the only significant difference was found in post-contrast T1 (p = 0.04). ICC showed moderate to excellent agreement in all measurements.

CONCLUSION

PTC performance was equivalent to ECG in terms of triggering consistency, image quality, and quantitative image measurements across multiple CMR applications.

摘要

背景

在心血管磁共振成像(CMR)过程中,心电图(ECG)信号容易受到梯度和射频干扰以及磁流体动力学效应的影响而发生失真。尽管导频音心脏(PTC)触发有潜力克服这些限制,但尚未确定其在各种CMR技术中的有效性。

目的

评估PTC触发在全面CMR检查中的性能。

方法

在两个中心招募了15名志愿者和20名患者。在部分序列中采集ECG触发图像以作比较。在电影采集过程中,根据ECG评估PTC触发的准确性。两名经验丰富的阅片者对PTC触发的电影、延迟钆增强(LGE)以及T1加权和T2加权黑血快速自旋回波(DB-TSE)图像的图像质量进行评分。比较使用PTC和ECG触发序列获得的定量心脏功能、血流和参数映射值。

结果

在15名志愿者和14名患者中采集了用于触发定时分析的屏气分段电影。3名志愿者和1名患者的PTC校准失败;1名患者的ECG触发记录失败。在总共1987次心跳中,发现3对PTC-ECG触发不匹配。图像质量评分显示PTC和ECG触发之间无显著差异。志愿者的定量测量结果无显著差异。在患者中,仅在对比剂后T1方面发现显著差异(p = 0.04)。组内相关系数(ICC)显示所有测量结果具有中度至高度一致性。

结论

在多种CMR应用中,PTC在触发一致性方面表现与ECG相当,图像质量和定量图像测量结果也与ECG相当。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a77/10350216/54d26278ae87/nihpp-rs3121723v1-f0001.jpg

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