Clemens M R, Schied H W, Waller H D
J Clin Chem Clin Biochem. 1986 Jun;24(6):369-74.
Cholesterol, triglycerides, and lipoproteins were studied in 23 alcoholics on admission for withdrawal therapy and after 4 weeks of abstinence. Lipoproteins were estimated quantitatively by lipoprotein electrophoresis. The results were used for the prediction of the risk of coronary heart disease. Half of the alcoholics had "high" or "elevated coronary risk" on admission for withdrawal. Abstinence resulted in decreased HDL-cholesterol concentrations in serum. Concurrently, the number of alcoholics with elevated coronary risk increased. This was mainly caused by high LDL-cholesterol levels on admission and after abstinence.
对23名接受戒酒治疗入院时及戒酒4周后的酗酒者进行了胆固醇、甘油三酯和脂蛋白的研究。通过脂蛋白电泳对脂蛋白进行定量评估。研究结果用于预测冠心病风险。一半的酗酒者在入院接受戒酒治疗时具有“高”或“升高的冠心病风险”。戒酒导致血清中高密度脂蛋白胆固醇浓度降低。同时,冠心病风险升高的酗酒者数量增加。这主要是由于入院时及戒酒之后低密度脂蛋白胆固醇水平较高所致。