From the Department of Pharmacy Practice (Alnajjar, Alhubaishi), and from the College of Pharmacy (Alnajjar, Alhubaishi, Alghamdi, Alomani, Abbas, Altammami, Alabdullatif, Bin Rokan), Princess Nourah bint Abdulrahman University; from the Medical Affairs, Department (Alzaben);, Sultan Bin Abdulaziz Humanitarian City; and from the Research and Scientific Center (Youssef), Sultan Bin Abdulaziz Humanitarian City, Riyadh, Kingdom of Saudi Arabia.
Saudi Med J. 2023 Jul;44(7):694-702. doi: 10.15537/smj.2023.44.7.20230080.
To assess the remission rate, metabolic changes, and quality of life after bariatric surgery among Saudi patients with type 2 diabetes (T2DM).
This cross-sectional study was conducted in 2 main centers in the Riyadh, Saudi Arabia. The study included patients with T2DM who underwent either laparoscopic sleeve gastrectomy (LSG) or Roux-en-Y gastric bypass (RYGB) surgery from 2014 to 2018. The remission rate was defined based on the American Diabetes Association (ADA) and the International Diabetes Federation (IDF) criteria. Quality of life was assessed using the World Health Organization Quality of Life (WHOQOL)-BREF.
A total of 232 patients were included with a mean age of 44.3 ± 10.3 years. 93.4% of the patients had LSG, while only 6.6% had RYGB surgery. Among patients who underwent either LSG or RYGB surgery, there was a significant improvement in metabolic and glycemic markers compared to the baseline. According to the ADA criteria, 48.5% of the patients had complete remission, while 18.9% had partial remission. Overall, 7% of the patients met the IDF optimization criteria, while 5.7% met the IDF improvement criteria. The mean score for all the QOL domains exceeded 63 ± 13, with the environmental and physical health domains having the highest scores.
Among Saudi patients, bariatric surgery was associated with high remission rates and a better quality of life.
评估沙特阿拉伯 2 型糖尿病（T2DM）患者接受减重手术后的缓解率、代谢变化和生活质量。
这是一项在沙特阿拉伯利雅得的 2 个主要中心进行的横断面研究。研究纳入了 2014 年至 2018 年间接受腹腔镜袖状胃切除术（LSG）或 Roux-en-Y 胃旁路术（RYGB）的 T2DM 患者。缓解率基于美国糖尿病协会（ADA）和国际糖尿病联合会（IDF）标准定义。使用世界卫生组织生活质量（WHOQOL）-BREF 评估生活质量。
共纳入 232 例患者，平均年龄为 44.3 ± 10.3 岁。93.4%的患者接受了 LSG，而仅 6.6%接受了 RYGB 手术。在接受 LSG 或 RYGB 手术的患者中，与基线相比，代谢和血糖标志物均有显著改善。根据 ADA 标准，48.5%的患者完全缓解，18.9%部分缓解。总体而言，7%的患者符合 IDF 优化标准，5.7%符合 IDF 改善标准。所有 QOL 领域的平均得分均超过 63 ± 13，其中环境和身体健康领域得分最高。
在沙特阿拉伯患者中，减重手术与较高的缓解率和更好的生活质量相关。
