泰国现役皇家泰陆军人员的脉压与体重指数之间的关系。

Relationship between pulse pressure and body mass index in active-duty Royal Thai Army personnel in Thailand.

机构信息

Department of Military and Community Medicine, Phramongkutklao College of Medicine, Bangkok, 10400, Thailand.

Department of Medicine, Phramongkutklao College of Medicine, Bangkok, 10400, Thailand.

出版信息

BMC Cardiovasc Disord. 2023 Jul 18;23(1):361. doi: 10.1186/s12872-023-03390-w.

DOI:10.1186/s12872-023-03390-w

PMID:37464282

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10355046/

Abstract

BACKGROUND

Elevated pulse pressure (PP) is a robust independent predictor of cardiovascular diseases. The relationship between PP and body mass index (BMI) was presented in a few studies. However, the findings were inconsistent. Therefore, the aim of the present study is to identify the association between elevated PP and BMI using a large sample of active-duty Royal Thai Army (RTA) personnel.

METHODS

A cross-sectional study was conducted through the use of the dataset obtained from the annual health examination database of RTA personnel in Thailand in 2022. BMI 25.0-29.9 kg/m was classified as obesity I, whereas BMI ≥ 30.0 kg/m was classified as obesity II. Elevated PP was defined as PP ≥ 50 mmHg. Multivariable linear regression and log-binomial regression models were utilized for determining the association between elevated PP and BMI.

RESULTS

A total of 62,113 active-duty RTA personnel were included in the study. The average BMI was 25.4 ± 3.8 kg/m, while the average PP was 50.1 ± 11.2 mmHg. Compared to individuals with normal weight, the [Formula: see text] coefficients of PP and BMI were 1.38 (95% CI: 1.15-1.60) and 2.57 (95% CI: 2.25-2.88) in individuals with obesity I and obesity II, respectively. Effect modification by high blood pressure (BP) on the association between elevated PP and BMI was observed. Among participants with normal BP, in comparison with BMI of 18.5-22.9 kg/m, the adjusted prevalence ratio (PR) for elevated PP was 1.23 (95% CI: 1.19-1.28) and 1.41 (95% CI: 1.35-1.48) in those with obesity I and obesity II, respectively. Meanwhile, among individuals with high BP, the adjusted PR for elevated PP was 1.05 (95% CI: 1.01-1.08) and 1.09 (95% CI: 1.06-1.13) in those with obesity I and obesity II, respectively.

CONCLUSION

PP was positively associated with BMI in active-duty RTA personnel. High BP was the modifier of the association between PP and BMI. A weaker association between elevated PP and BMI was observed among RTA personnel with high BP.

摘要

背景

脉压升高（PP）是心血管疾病的一个强有力的独立预测因子。已有少数研究探讨了 PP 与体重指数（BMI）之间的关系，但结果并不一致。因此，本研究旨在使用大量泰国皇家陆军（RTA）现役人员的样本，确定升高的 PP 与 BMI 之间的关联。

方法

本研究采用 2022 年泰国 RTA 人员年度健康检查数据库中的数据集进行横断面研究。BMI 为 25.0-29.9 kg/m2 被归类为肥胖 I，而 BMI≥30.0 kg/m2 被归类为肥胖 II。PP 升高定义为 PP≥50mmHg。多变量线性回归和对数二项式回归模型用于确定升高的 PP 与 BMI 之间的关联。

结果

共有 62113 名现役 RTA 人员纳入研究。平均 BMI 为 25.4±3.8 kg/m2，平均 PP 为 50.1±11.2mmHg。与正常体重者相比，肥胖 I 和肥胖 II 者的 PP 和 BMI 的[Formula: see text]系数分别为 1.38（95%CI：1.15-1.60）和 2.57（95%CI：2.25-2.88）。升高的 PP 与 BMI 之间的关联存在高血压（BP）的效应修饰。在正常血压的参与者中，与 BMI 为 18.5-22.9 kg/m2 相比，肥胖 I 和肥胖 II 者的升高 PP 的调整后患病率比（PR）分别为 1.23（95%CI：1.19-1.28）和 1.41（95%CI：1.35-1.48）。而在高血压患者中，肥胖 I 和肥胖 II 者的升高 PP 的调整后 PR 分别为 1.05（95%CI：1.01-1.08）和 1.09（95%CI：1.06-1.13）。