Camber Collective, Paris, France.
Camber Collective, Seattle, WA, USA.
Stud Fam Plann. 2023 Sep;54(3):523-538. doi: 10.1111/sifp.12248. Epub 2023 Jul 18.
Globally, there is a need for more family planning method options as currently, available options do not adequately meet the needs of women, specifically those who have infrequent sex. Levonorgestrel (LNG) 1.5 mg is widely available as emergency contraception pills (ECP), and recent research has shown that certain women take it as their main form of contraception. Furthermore, limited studies have found repeat, on-demand use safe and efficacious. This 12-month prospective, single-arm, interventional study in Ghana tested whether a single LNG 1.5 mg on-demand or pericoital ("around the time of sex") dose contraceptive was acceptable to women who have infrequent sex and if pharmacy provision was feasible. The study sample (1,890) comprised women of reproductive age recruited from urban areas, having infrequent sex (i.e., coital frequency ≤ 6× per month), and not using any other modern methods except condoms or ECP at the time of study inclusion. Results indicated that there is demand and acceptability for a pericoital pill and that pharmacy provision is feasible. Furthermore, precoital use of the pill had high levels of satisfaction and was popular with new users. Adding LNG 1.5 mg for pericoital use to the family planning method mix has the potential to address an important segment of the population currently underserved, decrease unwanted pregnancies, and increase modern contraceptive prevalence rates.
全球范围内,人们需要更多的计划生育方法选择,因为目前现有的方法并不能充分满足女性的需求,尤其是那些性生活不频繁的女性。左炔诺孕酮(LNG)1.5 毫克广泛用作紧急避孕药(ECP),最近的研究表明,某些女性将其作为主要的避孕方法。此外,有限的研究发现,重复按需使用是安全有效的。这项在加纳进行的为期 12 个月的前瞻性、单臂、干预性研究测试了单一剂量的 LNG 1.5 毫克按需或 peri-coital(“性行为前后”)避孕药对性生活不频繁的女性是否可接受,以及药房供应是否可行。研究样本(1890 名)包括从城市地区招募的育龄妇女,她们的性生活不频繁(即,性交频率≤每月 6 次),并且在研究纳入时除了避孕套或 ECP 外,不使用任何其他现代方法。结果表明,peri-coital 避孕药有需求和可接受性,药房供应是可行的。此外,避孕药的性交前使用满意度很高,深受新用户欢迎。将 LNG 1.5 毫克用于 peri-coital 用途添加到计划生育方法组合中,有可能解决目前服务不足的重要人群,减少意外怀孕,并提高现代避孕普及率。