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成人过敏性紫癜:一例报告

Henoch-Schönlein Purpura in the Adult, a Case Report.

作者信息

Virovets Ivan, Biggs Danielle

机构信息

Morristown Medical Center, Department of Emergency Medicine, Morristown, NJ.

出版信息

J Educ Teach Emerg Med. 2020 Jan 15;5(1):V20-V24. doi: 10.21980/J8QH08. eCollection 2020 Jan.

Abstract

UNLABELLED

This case report describes a dermatologic finding that is not typical in the adult population, but may be medically significant. A 39-year-old female patient with a past medical history that was negative for autoimmune disorders, vasculitides, or chronic infectious disease presented to our emergency department for evaluation of a painful rash on the bilateral lower extremities. She complained of two days of worsening raised, erythematous, pruritic and painful patches around both ankles, some of which had opened to become weeping sores. There was surrounding edema of both extremities. She denied any systemic symptoms. Online literature, primarily UpToDate was reviewed, and it was suspected that her rash may have been Henoch-Schönlein Purpura (HSP), given her lack of other medical history and a visual appearance that seemed consistent with the condition. To evaluate for renal involvement and systemic inflammation, labs were drawn and were grossly unremarkable except for a mild elevation in her C-reactive protein with a level of 37.6 mg/L. She was treated with intravenous (IV) hydration and IV ketorolac, with resultant symptomatic improvement. Since she did not have any apparent systemic involvement, she was discharged to follow up with rheumatology, with a recommendation to take over the counter non-steroidal anti-inflammatory drugs (NSAIDs). The patient was ultimately seen by rheumatology several months later, and a biopsy of the lesions demonstrated what appeared to be Henoch-Schönlein Purpura given her clinical presentation. Henoch-Schönlein Purpura can occur in adults, however rare, requiring close follow-up since in the adult population, it may result in renal failure and need for dialysis.

TOPICS

Rash, Henoch-Schönlein purpura, dermatology, nephrology, rheumatology, vasculitis.

摘要

未标注

本病例报告描述了一种在成人中不典型但可能具有医学意义的皮肤病学表现。一名39岁女性患者,既往无自身免疫性疾病、血管炎或慢性感染性疾病病史,因双侧下肢疼痛性皮疹前来我院急诊科就诊。她主诉双侧脚踝周围皮疹红肿、瘙痒、疼痛且逐渐加重已有两天,部分皮疹破溃形成渗液性溃疡。双下肢均有周围性水肿。她否认有任何全身症状。查阅了主要是UpToDate的在线文献,鉴于她没有其他病史且皮疹外观似乎与该病症相符,怀疑她的皮疹可能是过敏性紫癜(HSP)。为评估肾脏受累情况和全身炎症反应,进行了实验室检查,除C反应蛋白轻度升高至37.6mg/L外,其他检查结果大致正常。她接受了静脉补液和静脉注射酮咯酸治疗,症状有所改善。由于她没有明显的全身受累情况,出院后转诊至风湿病科,建议服用非处方非甾体抗炎药(NSAIDs)。几个月后该患者最终在风湿病科就诊,病变活检结果显示根据其临床表现符合过敏性紫癜。过敏性紫癜可发生于成人,尽管罕见,但由于在成人中可能导致肾衰竭及需要透析,故需要密切随访。

主题

皮疹、过敏性紫癜、皮肤病学、肾脏病学、风湿病学、血管炎。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/88be/10332541/a55e0ab5038b/jetem-5-1-v20f1.jpg

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