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儿童过敏性紫癜:皮质类固醇的作用

Henoch-Schonlein Purpura in Children: The Role of Corticosteroids.

作者信息

Kurnia Bella

机构信息

Podomoro Hermina Hospital, Jakarta, Indonesia.

出版信息

Open Access Maced J Med Sci. 2019 Jun 15;7(11):1812-1814. doi: 10.3889/oamjms.2019.538.

Abstract

BACKGROUND

Henoch-schonlein purpura (HSP) is an IgA-mediated systemic small vessel vasculitis. It is the most common form of systemic vasculitis in children.

CASE REPORT

A 9 years old girl admitted to the hospital with chief complain of purplish red rash on both legs since approximately 1 week with painful knees and ankles that make the patient unable to walk. The patient was diagnosed with HSP and was treated with corticosteroid and analgesics. The patients only stayed for 2 nights at the hospital and discharged from the hospital with the ability to walk and experience no pain.

CONCLUSION

The role of corticosteroids in the treatment of HSP is still controversial. But from various research, we can conclude that the role of corticosteroid in HSP is as a symptom reliever (reduce abdominal pain and arthritis), but does not slow the progression of renal disease.

摘要

背景

过敏性紫癜(HSP)是一种由免疫球蛋白A介导的全身性小血管血管炎。它是儿童最常见的全身性血管炎形式。

病例报告

一名9岁女孩因双下肢紫红色皮疹入院,主诉约1周前出现皮疹,同时伴有膝关节和踝关节疼痛,导致患者无法行走。该患者被诊断为过敏性紫癜,并接受了皮质类固醇和镇痛药治疗。患者仅在医院住了两晚,出院时能够行走且无疼痛。

结论

皮质类固醇在过敏性紫癜治疗中的作用仍存在争议。但从各种研究中,我们可以得出结论,皮质类固醇在过敏性紫癜中的作用是缓解症状(减轻腹痛和关节炎),但并不能减缓肾脏疾病的进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6352/6614272/6944740673bb/OAMJMS-7-1812-g001.jpg

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