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盆腔器官脱垂治疗后的生活质量:阴道子宫托与手术对比

Quality of Life After Treatment for Pelvic Organ Prolapse: Vaginal Pessary versus Surgery.

作者信息

Aimjirakul Komkrit, Pumtako Mintita, Manonai Jittima

机构信息

Department of Obstetrics & Gynaecology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

出版信息

Int J Womens Health. 2023 Jul 12;15:1017-1025. doi: 10.2147/IJWH.S406048. eCollection 2023.

DOI:10.2147/IJWH.S406048
PMID:37465722
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10350403/
Abstract

BACKGROUND

Pelvic organ prolapse (POP) is quite common and has an impact on quality of life (QoL). The evaluation of QoL after treatment for prolapse is important. The objective was to compare patient's prolapse symptoms, functional outcomes, and quality of life between pessary and surgery using standardized questionnaires at 1 and 6 months after treatment.

METHODS

We conducted a prospective study including women with symptomatic POP who chose pessary or surgery as the first-line treatment. We evaluated QoL using the International Consultation on Incontinence Questionnaire-Vaginal Symptoms and Prolapse Quality of Life questionnaires.

RESULTS

Seventy-two participants were enrolled, with 36 in each group. Body mass index, menopausal status, marital status, number of vaginal deliveries, and stage of pelvic organ prolapse were not significantly different between the groups. At 1 and 6 months after treatment, participants in both groups reported significant improvement in prolapse symptoms, functional outcomes, and overall quality of life. At 1 month after treatment, absolute changes in vaginal symptom scores in the pessary and surgery groups were -16.67 and -19.03, respectively (p > 0.05); at 6 months, the absolute changes were -19.21 and -19.25, respectively (p > 0.05). Significant improvement was only found in role limitation and physical and social domains at both follow-up times after surgery.

CONCLUSION

At 1 and 6 month(s) after treatment, women with symptomatic POP reported substantial improvement in prolapse symptoms and functional outcomes when treated with pessary or surgical correction.

摘要

背景

盆腔器官脱垂(POP)颇为常见,会对生活质量(QoL)产生影响。评估脱垂治疗后的生活质量很重要。目的是在治疗后1个月和6个月使用标准化问卷比较子宫托和手术治疗患者的脱垂症状、功能结局及生活质量。

方法

我们进行了一项前瞻性研究,纳入有症状的盆腔器官脱垂且选择子宫托或手术作为一线治疗的女性。我们使用国际尿失禁咨询委员会阴道症状问卷和脱垂生活质量问卷评估生活质量。

结果

共纳入72名参与者,每组36名。两组间体重指数、绝经状态、婚姻状况、阴道分娩次数及盆腔器官脱垂分期无显著差异。治疗后1个月和6个月,两组参与者的脱垂症状、功能结局及总体生活质量均有显著改善。治疗后1个月,子宫托组和手术组阴道症状评分的绝对变化分别为-16.67和-19.03(p>0.05);6个月时,绝对变化分别为-19.21和-19.25(p>0.05)。仅在手术后的两次随访中,角色限制以及身体和社会领域有显著改善。

结论

治疗后1个月和6个月,有症状的盆腔器官脱垂女性在接受子宫托或手术矫正治疗后,脱垂症状和功能结局有显著改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d925/10350403/735792871793/IJWH-15-1017-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d925/10350403/29c99932fef8/IJWH-15-1017-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d925/10350403/735792871793/IJWH-15-1017-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d925/10350403/29c99932fef8/IJWH-15-1017-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d925/10350403/735792871793/IJWH-15-1017-g0002.jpg

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本文引用的文献

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Int Urogynecol J. 2022 Oct;33(10):2603-2631. doi: 10.1007/s00192-022-05315-1. Epub 2022 Aug 18.
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Pessaries (mechanical devices) for managing pelvic organ prolapse in women.用于治疗女性盆腔器官脱垂的子宫托(机械装置)。
Cochrane Database Syst Rev. 2020 Nov 18;11(11):CD004010. doi: 10.1002/14651858.CD004010.pub4.
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Pelvic Organ Prolapse.
真实世界研究中盆腔器官脱垂治疗后的生活质量:建议、阴道子宫托及手术
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盆腔器官脱垂
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Effectiveness of ring pessaries versus vaginal hysterectomy for advanced pelvic organ prolapse. A cohort study.环状子宫托与经阴道子宫切除术治疗重度盆腔器官脱垂的疗效比较:一项队列研究
Int Urogynecol J. 2019 Dec;30(12):2161-2169. doi: 10.1007/s00192-019-03919-8. Epub 2019 Mar 12.
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Dysfunction, activity limitations, participation restriction and contextual factors in South African women with pelvic organ prolapse.南非盆腔器官脱垂女性的功能障碍、活动受限、参与限制及情境因素
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