Clinical Centre of Montenegro, Podgorica, Montenegro.
Clinic for Neurology and Psychiatry for Children and Youth, Belgrade, Serbia.
J Atten Disord. 2023 Dec;27(14):1662-1669. doi: 10.1177/10870547231187150. Epub 2023 Jul 19.
Complete or major symptoms of ADHD are often present in epilepsy. This study evaluated inattention and hyperactivity symptoms over the first 6 months in newly diagnosed pediatric epilepsy without comorbid ADHD.
Children and adolescents with newly diagnosed epilepsy were followed for 6 months after starting antiseizure medications. The Nisonger Child Behavior Rating Form (NCBRF), Adverse Event Profile (AEP), and the Revised Wechsler Intelligence Scale for Children were used.
There was a marked increase in attention difficulties while a moderate increase in hyperactivity levels. AEP scores, changes in non-verbal aspects of intelligence, levels of hyperactivity at the follow-up, and attention at baseline were significant predictors for inattention. In contrast, only levels of hyperactivity at the baseline and inattention at the follow-up were significant predictors for hyperactivity.
Significant inattention and hyperactivity levels originated 6 months after the diagnosis of epilepsy and starting antiseizure medication.
癫痫患者常存在注意缺陷多动障碍（ADHD）的完全或主要症状。本研究评估了新诊断的无共患 ADHD 的儿科癫痫患者在开始抗癫痫药物治疗后的前 6 个月内的注意力不集中和多动症状。
在开始抗癫痫药物治疗后，对新诊断的癫痫儿童和青少年进行了 6 个月的随访。使用了尼松格儿童行为评定量表（NCBRF）、不良事件概况（AEP）和修订版韦氏儿童智力量表。
在注意困难方面有明显增加，而在多动水平方面有中度增加。AEP 评分、非言语智力方面的变化、随访时的多动水平以及基线时的注意力是注意力不集中的显著预测因素。相比之下，只有基线时的多动水平和随访时的注意力不集中是多动的显著预测因素。
在癫痫诊断和开始抗癫痫药物治疗后 6 个月出现显著的注意力不集中和多动水平。
