Amsterdam UMC, University of Amsterdam, Department of Orthopedic Surgery, Amsterdam Movement Sciences, PO Box 22660, 1100 DD, Amsterdam, Netherlands; Academic Centre for Evidence-based Sports Medicine (ACES), PO Box 22660, 1100 DD, Amsterdam, the Netherlands; Amsterdam Collaboration for Health and Safety in Sports (ACHSS), AMC/VUmc IOC Research Centre, PO Box 22660, 1100 DD, Amsterdam, the Netherlands.
Spaarne Gasthuis Academy, Orthopedic Department, Spaarne Ziekenhuis, 2134 TM, Hoofddorp, the Netherlands; Specialised Center of Orthopedic Research and Education (stichting SCORE), Xpert Clinics, Orthopedic Department, 2134 TM, Hoofddorp, the Netherlands.
J ISAKOS. 2023 Oct;8(5):345-351. doi: 10.1016/j.jisako.2023.07.003. Epub 2023 Jul 17.
The American Orthopaedic Foot and Ankle score (AOFAS) is an outcome measure for ankle and hindfoot conditions, which requires scoring from both the patients and the physician. A completely patient-reported version has been developed and used before, but its measurements properties are unknown. Our goal was to determine the measurement properties and the minimally important change (MIC) of a completely patient-reported AOFAS (PR-AOFAS) in patients with ankle osteoarthritis. Additionally, the MIC of both the PR-AOFAS and the AOFAS was estimated, which had not previously been done.
The PR-AOFAS of 112 patients was evaluated for reliability, construct validity (using the AOFAS, Foot and Ankle Outcome Score, Ankle Osteoarthritis Score, Visual Analogue Scale, and Short Form-36), and responsiveness. The MIC was estimated using the optimal cut-off point of the receiver operating characteristic curve. This was a substudy of a randomized clinical trial on the efficacy of platelet-rich plasma injections for ankle osteoarthritis (OA).
The PR-AOFAS had sufficient construct validity, internal consistency, test-retest reliability, and responsiveness. The smallest detectable change at group level was 2.34. The MIC was 6.5 points (95% confidence interval: 0.6-14.4).
The measurement properties of the Dutch PR-AOFAS were sufficient in patients with ankle osteoarthritis who are willing to participate in a trial on injection therapy. The minimally important change of the PR-AOFAS is smaller than its smallest detectable change, making it more suitable for use in groups of patients, such as a research setting.
美国矫形足踝协会评分(AOFAS)是一种踝关节和后足疾病的疗效评估方法,需要患者和医生同时进行评分。目前已经开发出一种完全基于患者报告的版本并已被使用,但它的测量特性尚不清楚。我们的目标是确定一种完全基于患者报告的 AOFAS(PR-AOFAS)在踝关节骨关节炎患者中的测量特性和最小临床重要变化(MIC)。此外,还估计了 PR-AOFAS 和 AOFAS 的 MIC,这在以前尚未进行过。
评估了 112 例患者的 PR-AOFAS 的可靠性、结构有效性(使用 AOFAS、足踝结局评分、踝关节骨关节炎评分、视觉模拟量表和简明健康调查问卷)和反应性。MIC 使用最佳截断值的受试者工作特征曲线来估计。这是一项关于富血小板血浆注射治疗踝关节骨关节炎(OA)疗效的随机临床试验的子研究。
PR-AOFAS 具有足够的结构有效性、内部一致性、测试-重测可靠性和反应性。组水平的最小可检测变化为 2.34。MIC 为 6.5 分(95%置信区间:0.6-14.4)。
在愿意参加注射治疗试验的踝关节骨关节炎患者中,荷兰 PR-AOFAS 的测量特性是足够的。PR-AOFAS 的 MIC 比其最小可检测变化小,使其更适合于患者群体的使用,例如研究环境。