House dust mite disrupts the airway epithelial barrier by affecting the expression of thymic stromal lymphopoietin through inducing Atg5.
作者信息
Zhou Zicong, Liang Shixiu, Zhou Zili, Liu Jieyi, Meng Xiaojing, Liu Laiyu, Zou Fei, Yu Changhui, Cai Shaoxi
机构信息
Department of Respiratory and Critical Care Medicine, Chronic Airways Diseases Laboratory, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, China.
Department of Allergy and Clinical Immunology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510120, China.
出版信息
Chin Med J (Engl). 2023 Sep 5;136(17):2128-2130. doi: 10.1097/CM9.0000000000002615.
Abstract
摘要
相似文献
1
House dust mite disrupts the airway epithelial barrier by affecting the expression of thymic stromal lymphopoietin through inducing Atg5.屋尘螨通过诱导自噬相关蛋白5（Atg5）影响胸腺基质淋巴细胞生成素的表达，从而破坏气道上皮屏障。
Chin Med J (Engl). 2023 Sep 5;136(17):2128-2130. doi: 10.1097/CM9.0000000000002615.
2
Distinct roles of short and long thymic stromal lymphopoietin isoforms in house dust mite-induced asthmatic airway epithelial barrier disruption.短型和长型胸腺基质淋巴细胞生成素异构体在屋尘螨诱导的哮喘气道上皮屏障破坏中的不同作用。
Sci Rep. 2016 Dec 20;6:39559. doi: 10.1038/srep39559.
3
[1,25-dihydroxyvitamin D3 pretreatment inhibits house dust mite-induced thymic stromal lymphopoietin release by human airway epithelial cells].[1,25-二羟基维生素D3预处理可抑制屋尘螨诱导的人气道上皮细胞胸腺基质淋巴细胞生成素释放]
Nan Fang Yi Ke Da Xue Xue Bao. 2014 Apr;34(4):492-6.
4
House dust mites stimulate thymic stromal lymphopoietin production in human bronchial epithelial cells and promote airway remodeling through activation of PAR2 and ERK signaling pathway.屋尘螨通过激活 PAR2 和 ERK 信号通路刺激人支气管上皮细胞产生胸腺基质淋巴细胞生成素，并促进气道重塑。
Sci Rep. 2024 Nov 19;14(1):28649. doi: 10.1038/s41598-024-79226-0.
5
Short isoform thymic stromal lymphopoietin reduces inflammation and aerobic glycolysis of asthmatic airway epithelium by antagonizing long isoform thymic stromal lymphopoietin.短异构体胸腺基质淋巴细胞生成素通过拮抗长异构体胸腺基质淋巴细胞生成素减轻哮喘气道上皮的炎症和有氧糖酵解。
Respir Res. 2022 Mar 29;23(1):75. doi: 10.1186/s12931-022-01979-x.
6
IL-37 alleviates house dust mite-induced chronic allergic asthma by targeting TSLP through the NF-κB and ERK1/2 signaling pathways.IL-37 通过靶向 TSLP 抑制 NF-κB 和 ERK1/2 信号通路缓解屋尘螨诱导的慢性变应性哮喘。
Immunol Cell Biol. 2019 Apr;97(4):403-415. doi: 10.1111/imcb.12223. Epub 2019 Jan 23.
7
Involvement of autophagy in exacerbation of eosinophilic airway inflammation in a murine model of obese asthma.自噬在肥胖型哮喘小鼠模型中嗜酸性气道炎症恶化中的作用。
Autophagy. 2022 Sep;18(9):2216-2228. doi: 10.1080/15548627.2022.2025571. Epub 2022 Jan 31.
8
CBX4 Regulates Long-Form Thymic Stromal Lymphopoietin-mediated Airway Inflammation through SUMOylation in House Dust Mite-induced Asthma.CBX4 通过 SUMOylation 调控屋尘螨诱导的哮喘中长型胸腺基质淋巴细胞生成素介导的气道炎症。
Am J Respir Cell Mol Biol. 2022 Jun;66(6):648-660. doi: 10.1165/rcmb.2021-0301OC.
9
Local receptor-interacting protein kinase 2 inhibition mitigates house dust mite-induced asthma.局部受体相互作用蛋白激酶 2 抑制减轻屋尘螨诱导的哮喘。
Eur Respir J. 2024 Oct 3;64(4). doi: 10.1183/13993003.02288-2023. Print 2024 Oct.
10
Exposure to multi-walled carbon nanotubes results in aggravation of airway inflammation and remodeling and in increased production of epithelium-derived innate cytokines in a mouse model of asthma.暴露于多壁碳纳米管会导致哮喘小鼠模型中的气道炎症和重塑加重，并导致上皮细胞衍生的固有细胞因子产生增加。
Arch Toxicol. 2014 Feb;88(2):489-99. doi: 10.1007/s00204-013-1116-3. Epub 2013 Aug 15.
引用本文的文献
1
Application of Biologics in the Treatment of Asthma in the Past Two Decades: A Bibliometric Analysis and Beyond.过去二十年生物制剂在哮喘治疗中的应用：文献计量分析及其他
J Asthma Allergy. 2025 May 19;18:779-793. doi: 10.2147/JAA.S514250. eCollection 2025.
本文引用的文献
1
TSLP up-regulates inflammatory responses through induction of autophagy in T cells.TSLP 通过诱导 T 细胞自噬来上调炎症反应。
FASEB J. 2022 Feb;36(2):e22148. doi: 10.1096/fj.202101447R.
2
The dual roles of autophagy in gliomagenesis and clinical therapy strategies based on autophagic regulation mechanisms.自噬在胶质瘤发生中的双重作用及基于自噬调控机制的临床治疗策略。
Biomed Pharmacother. 2019 Dec;120:109441. doi: 10.1016/j.biopha.2019.109441. Epub 2019 Sep 18.
3
Distinct roles of short and long thymic stromal lymphopoietin isoforms in house dust mite-induced asthmatic airway epithelial barrier disruption.短型和长型胸腺基质淋巴细胞生成素异构体在屋尘螨诱导的哮喘气道上皮屏障破坏中的不同作用。
Sci Rep. 2016 Dec 20;6:39559. doi: 10.1038/srep39559.
4
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis.全基因组关联研究确定了克罗恩病新的易感基因座，并表明自噬参与疾病发病机制。
Nat Genet. 2007 May;39(5):596-604. doi: 10.1038/ng2032. Epub 2007 Apr 15.
Zotero 插件