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CO2 激光与微型动力系统在儿童复发性呼吸道乳头状瘤病治疗中的作用。

Role Of CO2 Laser & Microdebrider In The Treatment Of Juvenile Onset Recurrent Respiratory Papillomatosi.

机构信息

Department of ENT, Combined Military Hospital, Kharian, Pakistan.

Department of Radiology, Combined Military Hospital, Kharian, Pakistan.

出版信息

J Pak Med Assoc. 2023 Jul;73(7):1370-1373. doi: 10.47391/JPMA.3959.

DOI:10.47391/JPMA.3959
PMID:37469046
Abstract

OBJECTIVE

To compare the efficacy of two main treatment modalities of microdebrider and carbon dioxide laser excision for juvenile onset recurrent respiratory papillomatosis.

METHODS

The retrospective study was conducted in May 2021 at the Combined Military Hospital, Kharian, Pakistan, and comprised data from July 1, 2007, to January 31, 2020, of patients of either gender aged 2-12 years who were treated for juvenile onset recurrent respiratory papillomatosis either with microdebrider excision in group A or carbon dioxide laser excision in group B. Extent and severity of disease was documented as per the Derkay-Coltrera grading system. Data was analysed using SPSS 20.

RESULTS

Of the 39 patients, 23(59%) were girls and 16(41%) were boys. The overall mean age at the time of procedure was 6.62±2.06 years. Group A had 22(56.4%) subjects; 15(68.2%) girls and 7(31.8%) boys, while group B had 17(43.6%) cases; 8(47%) girls and 9(53%) boys. The mean operative time for group A was 40.91±11.50 minutes and for group B it was 60.59±19.51 minutes. Postoperative breathing and oedema status was better for group A (p<0.05), while there was no significant difference regarding postoperative pain, residual disease and repeat surgeries (p>0.05).

CONCLUSIONS

Microdebrider was found to be superior to carbon dioxide laser excision in the treatment of juvenile onset recurrent respiratory papillomatosis.

摘要

目的

比较微动力切除术和二氧化碳激光切除术两种主要治疗方式治疗青少年复发性呼吸道乳头瘤病的疗效。

方法

本回顾性研究于 2021 年 5 月在巴基斯坦卡拉里联合军事医院进行,纳入 2007 年 7 月 1 日至 2020 年 1 月 31 日期间因青少年复发性呼吸道乳头瘤病在 A 组接受微动力切除术或 B 组接受二氧化碳激光切除术治疗的 2-12 岁男女患者的资料。根据 Derkay-Coltrera 分级系统记录疾病的严重程度和严重程度。使用 SPSS 20 对数据进行分析。

结果

39 例患者中,23 例(59%)为女孩,16 例(41%)为男孩。手术时的平均年龄为 6.62±2.06 岁。A 组 22 例(56.4%);15 例(68.2%)为女孩,7 例(31.8%)为男孩,B 组 17 例(43.6%);8 例(47%)为女孩,9 例(53%)为男孩。A 组的平均手术时间为 40.91±11.50 分钟,B 组为 60.59±19.51 分钟。A 组术后呼吸和水肿状况较好(p<0.05),而术后疼痛、残留疾病和重复手术无显著差异(p>0.05)。

结论

在治疗青少年复发性呼吸道乳头瘤病方面,微动力切除术优于二氧化碳激光切除术。

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引用本文的文献

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Chinese guideline for the diagnosis and treatment of juvenile-onset recurrent respiratory papillomatosis (2024).《儿童复发性呼吸道乳头状瘤病诊断与治疗中国专家共识(2024年版)》
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Chinese guideline for the diagnosis and treatment of juvenile-onset recurrent respiratory papillomatosis (2024).《儿童复发性呼吸道乳头状瘤病诊断与治疗中国专家共识(2024年版)》
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