4th Year MBBS Student, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
ENT Department, Dr Ruth KM Pfau Civil Hospital, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
J Pak Med Assoc. 2023 Jul;73(7):1560-1562. doi: 10.47391/JPMA.7247.
External auditory canal carcinoma, while starting out as a seemingly benign condition, if left untreated can have an aggressive course of disease and involve multiple lower cranial nerves. Squamous cell carcinoma remains the most frequent histological type of malignant neoplasm of the external auditory canal and temporal bone. Here we describe a patient with a history of chronic suppurative otitis media with an extensive spread, the tumour was reaching from the skull base to the oropharynx involving neurovasculature along with soft tissues and bones, as well as the cerebellum. The involvement of the recurrent laryngeal and hypoglossal nerves were the most unusual presentation here. The case differed from all previous reported cases as the spinal accessory nerve was to spared. Surgery and radiotherapy are the treatment options but for the inoperable cases presenting with an already poor prognosis, concomitant radiotherapy is the only choice.
外耳道癌,虽然一开始似乎是良性的,但如果不治疗,可能会有侵袭性的病程,并涉及多个颅神经。鳞状细胞癌仍然是外耳道和颞骨恶性肿瘤最常见的组织学类型。在这里,我们描述了一名患有慢性化脓性中耳炎病史的患者,其肿瘤广泛扩散,肿瘤从颅底延伸到口咽,涉及神经血管、软组织和骨骼,以及小脑。喉返神经和舌下神经受累是这里最不寻常的表现。与之前所有报道的病例不同,副神经没有受累。手术和放疗是治疗选择,但对于已经预后不良的不可手术病例,联合放疗是唯一的选择。