Thys Erika, Sasse Kent
From the Reno School of Medicine, University of Nevada, Reno, NV, USA (ET, KS).
Nevada Surgical Associates, Reno, NV, USA (KS).
Int J MS Care. 2023 Jul-Aug;25(4):163-167. doi: 10.7224/1537-2073.2022-027. Epub 2023 Feb 8.
Urinary incontinence (UI) and fecal incontinence (FI) are challenging manifestations of multiple sclerosis (MS) that have historically been treated with limited success. Sacral neuromodulation (SNM) has provided successful resolution of UI and FI in the general population and in patients with neurologic conditions, including MS. We report on 6 patients with MS-related incontinence treated successfully with SNM and review the literature.
Medical records were reviewed retrospectively to identify patients with MS seeking treatment for incontinence. Six patients were identified, and each is presented with follow-up assessment of the severity of UI or FI.
All 6 individuals with MS had severe incontinence that had been refractory to therapies that included medications and pelvic floor physical therapy. Five patients reported severe UI and 2 patients reported severe FI. Each patient was successfully treated with SNM, with large reductions of incontinence scores and improved quality of life.
In this case series, SNM was effective as a treatment for UI and FI among patients with MS. These findings confirm other published series that have reported the success of SNM in patients with MS with incontinence. Sacral neuromodulation should be considered as a potential treatment option for patients with MS and UI and/or FI.
尿失禁(UI)和粪失禁(FI)是多发性硬化症(MS)的挑战性表现,以往治疗效果有限。骶神经调节(SNM)已成功解决了普通人群以及包括MS在内的神经系统疾病患者的UI和FI问题。我们报告了6例经SNM成功治疗的MS相关性失禁患者,并对文献进行了综述。
回顾性审查病历,以确定寻求失禁治疗的MS患者。确定了6例患者,并对每例患者进行了UI或FI严重程度的随访评估。
所有6例MS患者均有严重失禁,对包括药物治疗和盆底物理治疗在内的治疗均无效。5例患者报告有严重UI,2例患者报告有严重FI。每位患者均通过SNM成功治疗,失禁评分大幅降低,生活质量得到改善。
在本病例系列中,SNM对MS患者的UI和FI治疗有效。这些发现证实了其他已发表的系列研究,这些研究报告了SNM对MS失禁患者的治疗成功。骶神经调节应被视为MS合并UI和/或FI患者的潜在治疗选择。