一例晚期系统性肥大细胞增多症患者发生的高危急性髓系白血病病例。
A case of high-risk AML in a patient with advanced systemic mastocytosis.
作者信息
Fazio Manlio, Vetro Calogero, Markovic Uroš, Duminuco Andrea, Parisi Marina, Maugeri Cinzia, Mauro Elisa, Parrinello Nunziatina Laura, Stagno Fabio, Villari Loredana, Triolo Anna Maria, Stella Stefania, Palumbo Giuseppe A, Di Raimondo Francesco, Romano Alessandra, Zanotti Roberta
机构信息
Post Graduation School of Hematology University of Catania, A.O.U. Policlinico "G.Rodolico-San Marco" Catania Italy.
Division of Hematology A.O.U. Policlinico "G.Rodolico-San Marco" Catania Italy.
出版信息
Clin Case Rep. 2023 Jul 17;11(7):e7134. doi: 10.1002/ccr3.7134. eCollection 2023 Jul.
Aggressive SM + AML has limited therapeutic options. Even a strong combination of decitabine-venetoclax-midostaurin has a transient effect on AML and a mitigated effect on SM. Larger series are required to identify the best therapeutic strategy.
侵袭性系统性肥大细胞增多症合并急性髓系白血病（Aggressive SM + AML）的治疗选择有限。即使是地西他滨-维奈克拉-米哚妥林的强效联合用药对急性髓系白血病也只有短暂疗效，对系统性肥大细胞增多症的疗效也较弱。需要更大规模的病例系列研究来确定最佳治疗策略。
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