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大鼠心脏静脉瓣的形态发生。I. 光镜和扫描电镜观察

Morphogenesis of the venous valves in the rat heart. I. Light and scanning electron microscopy.

作者信息

Rogers C S

出版信息

J Submicrosc Cytol. 1986 Jul;18(3):501-8.

PMID:3746967
Abstract

Hearts from rat embryos ranging from 12.5 days gestation through birth were studied with light and scanning electron microscopy. Both valves of the sinus venosus are very prominent structures in the right atrium of the developing rat heart. The right venous valve is large and undulating and extends to the right atrioventricular canal. Many nodules are apparent on the surface of this valve by the thirteenth day. These nodules decrease in number as development progresses. The left venous valve is considerably smaller than the right. Neither valve shows signs of regression, and just prior to birth, both valves are very prominent. The right valve is so large that it almost divides the right atrium into two chambers. Based on these observations the rat may serve as a model for cor triatriatum dexter.

摘要

对妊娠12.5天至出生的大鼠胚胎心脏进行了光镜和扫描电镜研究。静脉窦的两个瓣膜在发育中的大鼠心脏右心房中是非常突出的结构。右静脉瓣大且呈波浪状,延伸至右房室管。到第13天时,该瓣膜表面可见许多小结节。随着发育进程,这些小结节数量减少。左静脉瓣比右静脉瓣小得多。两个瓣膜均未显示退化迹象,在出生前,两个瓣膜都非常突出。右瓣膜非常大,几乎将右心房分成两个腔室。基于这些观察结果,大鼠可作为右心三房心的模型。

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