Woody R C, Kearns G L, Brewster M A, Turley C P, Sharp G B, Lake R S
J Toxicol Clin Toxicol. 1986;24(4):305-19. doi: 10.3109/15563658608992595.
Cyclotrimethylenetrinitramine (RDX) is a highly explosive compound frequently used for both military and civilian purposes. Previously reported cases of human RDX intoxication were limited to wartime settings and have described no human pharmacokinetic data. We report the first human intoxication to occur in a non-wartime setting. This intoxication presented with status epilepticus in a child and permitted the description of RDX human pharmacokinetics. It also suggested a strong association between central nervous system dysfunction and RDX intoxication.
环三亚甲基三硝胺（RDX）是一种高爆炸性化合物，常用于军事和民用目的。先前报道的人类RDX中毒病例仅限于战时情况，且未描述任何人体药代动力学数据。我们报告了首例发生在非战时环境中的人类中毒事件。该中毒事件表现为一名儿童癫痫持续状态，从而得以描述RDX的人体药代动力学。这也表明中枢神经系统功能障碍与RDX中毒之间存在密切关联。
