Formicola A J, Deasy M J, Johnson D H, Howe E E
J Periodontol. 1979 Apr;50(4):207-11. doi: 10.1902/jop.1979.50.4.207.
The primary purpose of this study was to determine the amount of tooth staining produced by an alexidine mouthrinse. One hundred and eighty subjects rinsed twice daily for 1 month with either 15 ml of alexidine (0.035%) or a placebo solution. Prior to the study, the subjects were classified according to their smoking, coffee and tea drinking habits and these factors were subsequently considered in the analysis of the stain scores. Additionally, the effects on staining of a prior prophylaxis and the use of a fluoridated toothpaste during the study were determined. Upon termination of the study, subjects utilizing the active mouthrinse manifested a greater degree of staining than placebo users. The amount and intensity of the stain due to alexidine were not influenced (increased) by smoking, tea or coffee drinking habits. A prior prophylaxis did not reduce the staining propensity of alexidine users. The method of scoring developed can be used to assess the degree of tooth staining induced by antiplaque agents.
本研究的主要目的是确定洗必泰漱口水产生的牙齿染色量。180名受试者每天用15毫升洗必泰(0.035%)或安慰剂溶液漱口两次,持续1个月。在研究前,根据受试者的吸烟、喝咖啡和喝茶习惯进行分类,随后在分析染色分数时考虑这些因素。此外,还确定了先前的预防措施以及研究期间使用含氟牙膏对染色的影响。研究结束时,使用活性漱口水的受试者比使用安慰剂的受试者表现出更高程度的染色。洗必泰导致的染色量和强度不受吸烟、喝茶或喝咖啡习惯的影响(增加)。先前的预防措施并未降低洗必泰使用者的染色倾向。所开发的评分方法可用于评估防菌斑剂引起的牙齿染色程度。