Carlson H C, Porter K, Alms T H
J Periodontol. 1977 Apr;48(4):216-8. doi: 10.1902/jop.1977.48.4.216.
The alexidine mouthrinse used in this study (CP-101) is effective in reducing plaque. There was a reduction in gingivitis after 6-months use but not at a statistically significant level. An extrinsic brown stain occurred at a significant level on the teeth of participants using the active mouthrinse. Blood and urine laboratory results indicated that alexidine can be safely used over a 6-month period.
本研究中使用的洗必泰漱口水(CP-101)在减少牙菌斑方面有效。使用6个月后牙龈炎有所减轻,但未达到统计学显著水平。使用活性漱口水的参与者牙齿上出现了显著程度的外源性棕色染色。血液和尿液实验室结果表明,洗必泰在6个月期间可以安全使用。