Int J Periodontics Restorative Dent. 2024;44(5):498-509. doi: 10.11607/prd.6796.
The introduction of a new collagen substitute, which will potentially reduce the invasiveness of techniques by avoiding the need for a second surgical site (ie, the donor site), needs to be evaluated in relation to the surgical procedure that could benefit the most by utilizing such a matrix. This study compared the clinical outcomes following treatment of RT1 multiple adjacent gingival recessions (MAGRs) using the modified coronally advanced tunnel (MCAT) technique or the multiple coro- nally advanced flap (MCAF) in conjunction with a new volume-stable xenogeneic collagen matrix (VXCM). Secondarily, the study evaluated whether patients report a preference between the two surgical techniques in terms of discomfort. A total of 20 patients requiring treatment of MAGRs were randomly assigned to one of the two treatment groups: MCAF+VCMX (Group A) or MCAT+VCMX (Group B). The following measurements were recorded at baseline (before surgery) and at 6 and 12 months: gingival recession depth (REC), probing pocket depth (PD), keratinized tissue width (KTW), and gingival thickness (GT). Postoperative pain and discomfort were recorded using a visual analog scale (VAS) at 1 week. The primary outcome variable was mean root coverage (mRC), and second- ary outcomes were complete root coverage (CRC), changes in KTW and GT, patient discomfort and satisfaction, and duration of surgery. Healing was uneventful in both groups. At 12 months, both treatments resulted in statistically significant improvements in REC and GT compared to baseline (P < .05). The mRC was 79.95% ± 29.92% in the MCAF group and 64.74% ± 40.5% in the MCAT group (P = .124). CRC was seen in 65.6% of MCAF-treated sites and 52% of MCAT-treated sites (P = .181). Similar clinical results should be expected when MAGRs are treated with MCAF or MCAT, with the adjunct of VCMX.
引入一种新的胶原替代品，通过避免第二个手术部位（即供体部位）的需要，有可能减少技术的侵入性，需要评估该手术程序最有可能受益于这种基质。本研究比较了改良冠状推进隧道（MCAT）技术或多个冠状推进瓣（MCAF）联合新型体积稳定异种胶原基质（VXCM）治疗 RT1 多个相邻牙龈退缩（MAGR）的临床疗效。其次，研究评估了患者在两种手术技术的舒适度方面是否报告偏好。共 20 名需要治疗 MAGR 的患者被随机分配到以下两个治疗组之一：MCAF+VCMX（A 组）或 MCAT+VCMX（B 组）。在基线（手术前）和 6 个月和 12 个月时记录以下测量值：牙龈退缩深度（REC）、探诊袋深度（PD）、角化组织宽度（KTW）和牙龈厚度（GT）。术后疼痛和不适使用视觉模拟量表（VAS）在 1 周时记录。主要观察变量是平均根覆盖（mRC），次要观察变量是完全根覆盖（CRC）、KTW 和 GT 的变化、患者的不适和满意度以及手术持续时间。两组均无手术相关并发症。12 个月时，两种治疗方法均使 REC 和 GT 与基线相比均有统计学显著改善（P <.05）。MCAF 组的 mRC 为 79.95%±29.92%，MCAT 组为 64.74%±40.5%（P =.124）。MCAF 治疗组中有 65.6%的位点和 MCAT 治疗组中有 52%的位点出现 CRC（P =.181）。当 MAGR 用 MCAF 或 MCAT 治疗，并联合 VCMX 时，预计会有类似的临床结果。
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