Department of Biomedical and Neuromotor Sciences, University of Bologna, Via San Vitale 59, Bologna, Italy.
Department of Periodontics & Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI, USA.
Clin Oral Investig. 2020 Sep;24(9):3181-3191. doi: 10.1007/s00784-019-03192-5. Epub 2020 May 2.
To test the safety of a new volume-stable collagen matrix (VCMX) in combination with coronally advanced flap (CAF) for the treatment of single gingival recession.
Ten patients were treated for single RT1 gingival recession. Complete and mean root coverage, gingival thickness and keratinized tissue height, patient-reported outcome measures (PROMs), and safety were assessed up to 180 days. Descriptive statistics were used to analyze the clinical parameters.
VCMX resulted to be safe with no serious adverse events in all patients. At 6 months, root coverage was 96.7% with 90% of defects exhibiting complete coverage. There was an increase in mean width of keratinized tissue (KT) (0.4 ± 0.8 mm) and in gingival thickness (GT) (0.4 ± 0.34 mm); however, the difference was not statistically significant compared to baseline parameters. Pain perception and pain-killer consumption were low and decreasing further at 7 days. Esthetic satisfaction for both patients and experts revealed excellent scores.
VCMX is a safe and well-tolerated device for the treatment of single gingival recessions. In combination with CAF, it resulted in a high performance in terms of mean and complete root coverage, KT width, and GT increase. VCMX may reduce patient discomfort and post-operative morbidity.
VCMX is a safe and stable substitute for the treatment of gingival recession in conjunction with coronally advanced technique.
测试新型体积稳定型胶原基质(VCMX)联合冠向推进瓣(CAF)治疗单个牙龈退缩的安全性。
10 名患者接受了单个 RT1 牙龈退缩的治疗。在 180 天内评估了完全和平均根覆盖、牙龈厚度和角化组织高度、患者报告的结果测量(PROM)以及安全性。使用描述性统计分析临床参数。
所有患者均未出现严重不良事件,表明 VCMX 是安全的。6 个月时,根覆盖为 96.7%,90%的缺损表现为完全覆盖。角化组织(KT)的平均宽度(0.4±0.8mm)和牙龈厚度(GT)(0.4±0.34mm)均有所增加;然而,与基线参数相比,差异无统计学意义。疼痛感知和止痛药的使用量较低,并在 7 天时进一步下降。患者和专家对美观满意度均为优秀评分。
VCMX 是一种安全且耐受良好的治疗单个牙龈退缩的设备。与 CAF 联合使用,在平均和完全根覆盖、KT 宽度和 GT 增加方面表现出了优异的性能。VCMX 可能会减少患者的不适和术后发病率。
VCMX 是一种安全且稳定的替代物,可与冠向推进技术联合治疗牙龈退缩。