Kirsch Hanne, Krüger Paul-Christian, John-Kroegel Ulrike, Waginger Matthias, Mentzel Hans-Joachim
Section of Pediatric Radiology, Jena University Hospital Department of Diagnostic and Interventional Radiology, Jena, Germany.
Section of Pediatric Nephrology, University Hospital Jena Department of Pediatrics, Jena, Germany.
Rofo. 2023 Dec;195(12):1097-1105. doi: 10.1055/a-2099-5907. Epub 2023 Jul 6.
Functional MR urography (fMRU) has developed into an innovative, radiation-free option for assessing parameters of kidney function in pediatric radiology. The importance of fMRU in comparison to the standardized established nuclear medicine procedure (99mTc-Mercapto-acetyltriglycerine, MAG3 scintigraphy) is shown using SWOT analysis.
To assess the current state of research, a selective literature search was carried out in PubMed. Taking into account the current scientific status, the examination technique, preparation, and evaluation of fMRU are presented.
As a result of the comparison with MAG3, fMRU is suitable for certain indications and represents an optimal combination of morphological and functional representation of the kidneys and urinary tract, especially in the case of surgical consequences.
fMRU has been successfully established as a diagnostic method for assessing the morphology and function of the kidneys in competition with MAG3 scintigraphy.
· Functional MRU allows reliable statements on the morphology and function of the kidneys and urinary tract.. · The results of the functional assessment of fMRU are comparable to the results of MAG3 scintigraphy.. · The complex implementation and demanding evaluation limits the spread of fMRU as a complete alternative to MAG3 scintigraphy. fMRU is reserved for special indications.. · Functional MRU has prevailed over MAG3 scintigraphy for complex renal and urinary tract anomalies (CAKUT) that require surgical correction. An example is the clarification of dribbling in girls, which is usually based on an ectopic opening of a ureter in a double system..
· Kirsch H, Krüger P, John-Kroegel U et al. Functional MR urography in children - update 2023. Fortschr Röntgenstr 2023; 195: 1097 - 1105.
功能磁共振尿路造影(fMRU)已发展成为一种用于评估儿科放射学中肾功能参数的创新型无辐射检查方法。使用SWOT分析法展示了fMRU与标准化的核医学程序(99mTc-巯基乙酰三甘氨酸,MAG3闪烁扫描)相比的重要性。
为评估当前研究状况,在PubMed中进行了选择性文献检索。考虑到当前的科学现状,介绍了fMRU的检查技术、准备工作及评估。
与MAG3相比,fMRU适用于某些适应症,是肾脏和尿路形态与功能显示的最佳组合,尤其是在手术后果方面。
fMRU已成功确立为一种与MAG3闪烁扫描竞争的用于评估肾脏形态和功能的诊断方法。
· 功能磁共振尿路造影能够可靠地描述肾脏和尿路的形态与功能。· fMRU功能评估的结果与MAG3闪烁扫描的结果具有可比性。· 复杂的实施过程和严格的评估限制了fMRU作为MAG3闪烁扫描的完全替代方法的推广。fMRU仅用于特殊适应症。· 对于需要手术矫正的复杂肾和尿路异常(CAKUT),功能磁共振尿路造影已优于MAG3闪烁扫描。一个例子是澄清女孩的滴尿问题,这通常是由于双系统中输尿管的异位开口所致。
· Kirsch H, Krüger P, John-Kroegel U等。儿童功能磁共振尿路造影 - 2023年更新。Fortschr Röntgenstr 2023; 195: 1097 - 1105。