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6至10岁早发性脊柱侧弯(EOS)患者采用保留生长器械治疗与一期确定性融合治疗的疗效比较。

Comparison of treatment outcomes between growth-sparing instrumentation and definitive one-stage fusion for EOS patients ages 6-10 years.

作者信息

Johnston Charles E, Thornberg David C, Palmer Robert

机构信息

Department of Orthopedics, Scottish Rite for Children, 2222 Welborn Street, Dallas, TX, 75219, USA.

Pediatric Orthopedics of Southwest Florida, 341 Turnbury Way, Naples, FL, 34110, USA.

出版信息

Spine Deform. 2023 Nov;11(6):1529-1537. doi: 10.1007/s43390-023-00731-9. Epub 2023 Jul 22.

Abstract

PURPOSE

To compare objective outcomes for EOS patients age 6-10 years treated by growth-sparing (GS) surgery or definitive one-stage correction and fusion (DF).

METHODS

We reviewed surgical, radiographic, PFT's, and EOSQ-24 outcomes for EOS patients > age 6 at index surgery treated at a single institution, minimum 2-year follow-up. Neuromuscular diagnoses were excluded.

RESULTS

47 patients underwent index surgery between age 6 and 10.9 years. Twenty-one had DF, 26 had GS surgery (13 MCGR, 13 TGR). Diagnoses included 15 congenital, 15 idiopathic, 17 syndromic. Age at index was 9.1 years DF, 7.8 GS (p < .001). Follow-up was 63-78 months. 18/26 GS cases converted to DF, 13 due to complications, which occurred in 8/21 DF cases vs 19/26 GS (p = .016). DF patients had fewer post-index surgeries (0.6 vs 3.7, p < .001). At follow-up there were no differences in curve magnitudes, %correction, T1-12/T1-S1 segment lengths, EOSQ-24 scores or PFTs. 18 patients converting to DF after initial GS had equal outcomes as DF initially. 31 patients > age 8 at index ("tweeners") were studied separately. 13 had GS surgery (7 MCGR), 18 had DF. At > 60 months follow-up, curve magnitudes, spine lengths, PFT's, or EOSQ scores were equivalent. DF patients had fewer procedures and complications.

CONCLUSION

For patients age 6-10.9 years, outcomes were no different at > 5 year follow-up between DF and GS groups. DF patients had fewer total surgeries and complications. Equal outcomes also occurred for tweeners. As a result, GS treatment does not appear to benefit patients > age 8.

摘要

目的

比较采用保留生长(GS)手术或一期确定性矫正融合术(DF)治疗的6至10岁早发性脊柱侧弯(EOS)患者的客观疗效。

方法

我们回顾了在单一机构接受初次手术时年龄大于6岁的EOS患者的手术、影像学、肺功能测试(PFT)和EOSQ - 24评分结果,随访时间至少为2年。排除神经肌肉疾病诊断病例。

结果

47例患者在6至10.9岁之间接受了初次手术。21例行DF手术,26例行GS手术(13例MCGR,13例TGR)。诊断包括15例先天性、15例特发性、17例综合征性。初次手术时年龄DF组为9.1岁,GS组为7.8岁(p < 0.001)。随访时间为63至78个月。26例GS手术患者中有18例转为DF手术,13例是由于并发症,而21例DF手术患者中有8例出现并发症,GS组为19例(p = 0.016)。DF手术患者术后再次手术次数较少(0.6次对3.7次,p < 0.001)。随访时,在侧弯度数、矫正百分比、T1 - 12/T1 - S1节段长度、EOSQ - 24评分或肺功能测试方面无差异。最初接受GS手术后来转为DF手术的18例患者的疗效与最初行DF手术的患者相同。对初次手术时年龄大于8岁的31例患者(“中间型”)进行了单独研究。13例行GS手术(7例MCGR),18例行DF手术。在随访超过60个月时,侧弯度数、脊柱长度、肺功能测试或EOSQ评分相当。DF手术患者的手术和并发症较少。

结论

对于6至10.9岁的患者,在随访超过5年时,DF组和GS组的疗效无差异。DF手术患者的总手术次数和并发症较少。“中间型”患者的疗效也相当。因此,GS治疗似乎对年龄大于8岁的患者无益处。

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