Department of Radiology, Neuroradiology and Nuclear Medicine, Johannes Wesling University Hospital, Ruhr University Bochum, Bochum, Germany.
Siemens Healthineers, Erlangen, Germany.
Eur J Radiol. 2023 Sep;166:110983. doi: 10.1016/j.ejrad.2023.110983. Epub 2023 Jul 17.
Imaging stents and in-stent stenosis remains a challenge in coronary computed tomography angiography (CCTA). In comparison to conventional Computed Tomography, Photon Counting CT (PCCT) provides decisive clinical advantages, among other things by providing low dose ultra-high resolution imaging of coronary arteries. This work investigates the image quality in CCTA using clinically established kernels and those optimized for the imaging of cardiac stents in PCCT, both for in-vitro stent imaging in 400 μm standard resolution mode (SRM) and 200 μm Ultra High Resolution Mode (UHR).
Based on experimental scans, vascular reconstruction kernels (Bv56, Bv64, Bv72) were optimized. In an established phantom, 10 different coronary stents with 3 mm diameter were scanned in the first clinically available PCCT. Scans were reconstructed with clinically established and optimized kernels. Four readers measured visible stent lumen, performed ROI-based density measurements and rated image quality.
Regarding the visible stent lumen, UHR is significantly superior to SRM (p < 0.001). In all levels, the optimized kernels are superior to the clinically established kernels (p < 0.001). One optimized kernel showed a significant reduction of noise compared to the clinically established kernels. Overall image quality is improved with optimized kernels.
In a phantom study PCCT UHR with optimized kernels for stent imaging significantly improves the ability to assess the in-stent lumen of small cardiac stents. We recommend using UHR with an optimized sharp vascular reconstruction kernel (Bv72uo) for imaging of cardiac stent.
在冠状动脉计算机断层扫描血管造影(CCTA)中,对支架和支架内狭窄进行成像仍然是一个挑战。与传统计算机断层扫描相比,光子计数 CT(PCCT)提供了决定性的临床优势,除其他外,还可以对冠状动脉进行低剂量超高分辨率成像。本研究旨在使用临床既定的内核和专为 PCCT 中心脏支架成像优化的内核,分别对 400μm 标准分辨率模式(SRM)和 200μm 超高分辨率模式(UHR)下的 CCTA 中的图像质量进行研究。
基于实验扫描,对血管重建内核(Bv56、Bv64、Bv72)进行了优化。在一个既定的体模中,使用首次临床可用的 PCCT 对 10 种不同直径为 3mm 的冠状动脉支架进行扫描。使用临床既定的内核和优化的内核进行扫描重建。四位读者测量可见的支架内腔,进行基于 ROI 的密度测量并评估图像质量。
在可见的支架内腔方面,UHR 明显优于 SRM(p<0.001)。在所有层面上,优化的内核均优于临床既定的内核(p<0.001)。一个优化的内核与临床既定的内核相比,噪声显著降低。整体图像质量得到优化内核的改善。
在体模研究中,用于支架成像的 PCCT UHR 与优化的内核显著提高了评估小型心脏支架内腔的能力。我们建议使用 UHR 和优化的锐利血管重建内核(Bv72uo)进行心脏支架成像。