吉尔伯氏菌引起的恢复期 COVID-19 患者感染。

Infection caused by Cupriavidus gilardii in a convalescent COVID-19 patient.

机构信息

School of Clinical Medicine, Weifang Medical University, Wei Fang, China; Department of Respiratory and Critical Medicine, Qingdao Hospital, University of Health and Rehabilitation Sciences (Qingdao Municipal Hospital), Qingdao, China.

Department of Respiratory and Critical Medicine, Qingdao Hospital, University of Health and Rehabilitation Sciences (Qingdao Municipal Hospital), Qingdao, China; Respiratory Disease Key Laboratory of Qingdao, Qingdao Hospital, University of Health and Rehabilitation Sciences (Qingdao Municipal Hospital), Qingdao, China.

出版信息

Int J Infect Dis. 2023 Sep;134:287-289. doi: 10.1016/j.ijid.2023.07.015. Epub 2023 Jul 20.

DOI:10.1016/j.ijid.2023.07.015

PMID:37481110

Abstract

Cupriavidus gilardii is an aerobic, gram-negative bacillus that can opportunistically infect immunocompromised patients or those undergoing invasive procedures. We reported a case caused by C. gilardii in a previously basic healthy 78-year-old male, who had COVID-19 and had used corticosteroids recently. The bacterium was identified as C. gilardii by the metagenomic next-generation sequencing from the patient's bronchoalveolar lavage fluid and blood. In addition, this is the first time that we isolated C. gilardii from bronchoalveolar lavage fluid, which provides clinical experience in rare bacterial infections.

摘要

金氏杆菌是一种需氧、革兰氏阴性杆菌，可伺机感染免疫功能低下的患者或接受侵入性操作的患者。我们报告了一例由金氏杆菌引起的病例，患者为一名基本健康的 78 岁男性，患有 COVID-19 且近期使用了皮质类固醇。该细菌通过对患者支气管肺泡灌洗液和血液进行宏基因组下一代测序鉴定为金氏杆菌。此外，这是我们首次从支气管肺泡灌洗液中分离出金氏杆菌，为罕见细菌感染提供了临床经验。