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遗忘型行为性额颞叶痴呆和阿尔茨海默病中的情景记忆

Episodic Memory in Amnestic Behavioral Frontotemporal Dementia and Alzheimer's Disease.

作者信息

Bussè Cinzia, Zorzi Giovanni, Pettenuzzo Ilaria, Mozzetta Stefano, Cagnin Annachiara

机构信息

Department of Neurosciences (DNS), University of Padova, Padova, Italy.

Padova Neuroscience Center (PNC), University of Padova, Padova, Italy.

出版信息

J Alzheimers Dis Rep. 2023 Jun 12;7(1):605-612. doi: 10.3233/ADR-230015. eCollection 2023.

Abstract

Behavioral frontotemporal dementia (bvFTD) may present with episodic memory deficits. In 38 patients with bvFTD and 61 with Alzheimer's disease (AD) specific measures of verbal memory (learning curves and serial position effects) were studied through the Rey Auditory Verbal Learning test. Forty-two percent of bvFTD showed deficits of delayed recall memory similar to that found in AD including the serial position effects. Amnestic bvFTD had more severe atrophy in the left mesial temporal lobe than non-amnestic bvFTD. AD-like memory deficits are not infrequent in bvFTD and may be in part related to mesial temporal lobe atrophy.

摘要

行为性额颞叶痴呆(bvFTD)可能会出现情景记忆缺陷。通过雷伊听觉词语学习测试,对38例bvFTD患者和61例阿尔茨海默病(AD)患者的言语记忆特定指标(学习曲线和系列位置效应)进行了研究。42%的bvFTD患者表现出与AD患者相似的延迟回忆记忆缺陷,包括系列位置效应。遗忘型bvFTD患者左侧内侧颞叶的萎缩比非遗忘型bvFTD更严重。bvFTD中类似AD的记忆缺陷并不少见,可能部分与内侧颞叶萎缩有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d8/10357122/742b26e979ec/adr-7-adr230015-g001.jpg

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