Mellat-Ardakani Milad, Salahshour Faeze, Rafsanjani Katayoun, Avanaki Foroogh Alborzi, Azizi Maryam
Department of Radiology, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Department of Radiology, Advanced Diagnostic and Interventional Radiology Research Center (ADIR), Imam Khomeini Hospital Complex, Tehran University of Medical Sciences(TUMS), Tehran, Iran.
Radiol Case Rep. 2023 Jul 11;18(9):3291-3294. doi: 10.1016/j.radcr.2023.06.051. eCollection 2023 Sep.
Vanishing bile duct syndrome is a rare, acquired disease that has been described in different pathologic conditions' including adverse drug reactions, autoimmune diseases, graft vs host disease, and neoplasms. It is a condition characterized by progressive loss of intrahepatic bile ducts leading to ductopenia and cholestasis. Here we report a 27-year-old female who presented with jaundice and cholestatic hepatitis and was finally diagnosed with vanishing Bile duct syndrome secondary to Hodgkin lymphoma. Physicians need to consider a range of differential diagnoses, especially malignancies, in suspected cases of vanishing bile duct syndrome.
消失胆管综合征是一种罕见的后天性疾病，已在不同病理状况下被描述，包括药物不良反应、自身免疫性疾病、移植物抗宿主病和肿瘤。它是一种以肝内胆管进行性丧失导致胆管减少和胆汁淤积为特征的病症。在此，我们报告一名27岁女性，她出现黄疸和胆汁淤积性肝炎，最终被诊断为继发于霍奇金淋巴瘤的消失胆管综合征。对于疑似消失胆管综合征的病例，医生需要考虑一系列鉴别诊断，尤其是恶性肿瘤。
