Azizli Ali, Sargın Gökhan, Senturk Taskin
Department of Rheumatology, Faculty of Medicine, Aydin Adnan Menderes University, Aydın, Turkey.
J Rheum Dis. 2023 Apr 1;30(2):99-105. doi: 10.4078/jrd.22.0053. Epub 2023 Mar 17.
The sleep quality is worse in rheumatoid arthritis (RA) patients than in healthy controls and it is more difficult to achieve a satisfactory quality of life after treatment with age. Our aim is to assess the quality of life and sleep in elderly onset RA patients and to analyze the effect of disease-modifying agents on sleep and quality of life.
Thirty-four older patients with RA patients and 30 healthy controls are included in the study. Sleep quality was evaluated with the Pittsburg sleep quality index and quality of life with Short Form-36. Parametric/non-parametric tests and Spearman/Pearson correlation analysis were applied for the data according to the distribution.
While the rate of poor sleep quality before treatment was 67.6%, the rate was 26.5% after treatment. There was a statistically significant difference before and after treatment in terms of subjective sleep quality, sleep latency, sleep duration, sleep efficiency, and scores for sleep disturbance. The mean steroid dose and Disease Activity Score-28 were higher in patients with poor sleep quality than in patients with good sleep quality. Patients with poor sleep quality had lower mean physical function, pain, general health, social function, emotional role difficulties, and energy/vitality values than patients with good sleep quality.
Both sleep and quality of life improved after treatment in older patients with RA patients. In older patients, it should be regularly evaluated in terms of sleep and quality of life and appropriate treatment should be provided.
类风湿关节炎（RA）患者的睡眠质量比健康对照者差，且随着年龄增长，治疗后达到满意生活质量更加困难。我们的目的是评估老年发病RA患者的生活质量和睡眠情况，并分析改善病情药物对睡眠和生活质量的影响。
本研究纳入了34例老年RA患者和30例健康对照者。采用匹兹堡睡眠质量指数评估睡眠质量，采用简明健康调查问卷-36评估生活质量。根据数据分布情况，对数据应用参数/非参数检验以及Spearman/Pearson相关分析。
治疗前睡眠质量差的比例为67.6%，治疗后为26.5%。在主观睡眠质量、入睡潜伏期、睡眠时间、睡眠效率和睡眠障碍评分方面，治疗前后存在统计学显著差异。睡眠质量差的患者平均类固醇剂量和疾病活动评分-28高于睡眠质量好的患者。睡眠质量差的患者在平均身体功能、疼痛、总体健康、社会功能、情感角色困难以及精力/活力值方面低于睡眠质量好的患者。
老年RA患者治疗后睡眠和生活质量均有所改善。对于老年患者，应定期评估其睡眠和生活质量，并给予适当治疗。
