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类风湿关节炎患者睡眠质量差的患病率及相关因素:一项横断面研究。

Prevalence of Poor Sleep Quality and Associated Factors in Individuals with Rheumatoid Arthritis: A Cross-Sectional Study.

机构信息

División Académica de Ciencias de la Salud, Universidad Juárez Autónoma de Tabasco, Villahermosa 86100, Mexico.

Subdirección de Investigaciones Clínicas, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Ciudad de México 14370, Mexico.

出版信息

Medicina (Kaunas). 2023 Sep 8;59(9):1633. doi: 10.3390/medicina59091633.

Abstract

: Poor sleep quality has been frequently observed in individuals with rheumatoid arthritis. In the present study, we analyzed the presence of poor sleep quality in a sample of Mexican individuals with rheumatoid arthritis; then, we compared sociodemographic and clinical characteristics among patients to determine risk factors for poor sleep quality. : In this cross-sectional study, we included 102 individuals with rheumatoid arthritis from a hospital in Mexico. We evaluated disease activity (DAS28), quality of sleep using the Pittsburgh Sleep Quality Index, and the presence of depression and anxiety with the Hospital Anxiety and Depression Scale. We performed a Chi-square test and a -test. Then, we performed a logistic regressions model of the associated features in a univariable analysis. : Poor sleep quality was observed in 41.75% of the individuals with rheumatoid arthritis. Being married was a proactive factor (OR 0.04, 95% CI 0.1-0.9, = 0.04), whereas having one's hips affected or presenting with anxiety and depression was associated with poor sleep quality (OR 4.6, 95% CI 1.2-17.69, = 0.02). After a multivariate analysis, having anxiety (OR 5.0, 95% CI 1.4-17.7, < 0.01) and depression (OR 9.2, 95% CI 1.0-8.1, < 0.01) remained associated with a higher risk of having poor sleep quality. Other clinical characteristics among patients were not significantly different. : Our results showed that individuals with rheumatoid arthritis who also presented with depression or anxiety had a higher risk of suffering from poor sleep quality. However, more studies with larger samples are necessary to replicate these results in the Mexican population.

摘要

: 类风湿关节炎患者常伴有睡眠质量差。本研究分析了墨西哥类风湿关节炎患者睡眠质量差的情况,并比较了患者的社会人口学和临床特征,以确定睡眠质量差的危险因素。 : 在这项横断面研究中,我们纳入了来自墨西哥一家医院的 102 名类风湿关节炎患者。我们使用匹兹堡睡眠质量指数评估了睡眠质量,使用医院焦虑抑郁量表评估了抑郁和焦虑的发生情况。我们进行了卡方检验和 t 检验。然后,我们对单变量分析中的相关特征进行了逻辑回归模型分析。 : 41.75%的类风湿关节炎患者存在睡眠质量差的情况。已婚是一个积极因素(OR 0.04,95%CI 0.1-0.9, = 0.04),而髋关节受影响或出现焦虑和抑郁与睡眠质量差有关(OR 4.6,95%CI 1.2-17.69, = 0.02)。多变量分析后,焦虑(OR 5.0,95%CI 1.4-17.7, < 0.01)和抑郁(OR 9.2,95%CI 1.0-8.1, < 0.01)与睡眠质量差的风险增加相关。患者的其他临床特征无显著差异。 : 我们的结果表明,同时患有抑郁或焦虑的类风湿关节炎患者睡眠质量差的风险更高。然而,需要更多具有更大样本量的研究来复制这些结果在墨西哥人群中的应用。

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