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生存分析、Kaplan-Meier曲线和Cox回归:基本概念

Survival Analysis, Kaplan-Meier Curves, and Cox Regression: Basic Concepts.

作者信息

Andrade Chittaranjan

机构信息

Dept. of Clinical Psychopharmacology and Neurotoxicology, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.

出版信息

Indian J Psychol Med. 2023 Jul;45(4):434-435. doi: 10.1177/02537176231176986. Epub 2023 Jun 11.

Abstract

Survival analysis is used to analyze data from patients who are followed for different periods of time and in whom the outcome of interest, a dichotomous event, may or may not have occurred at the time the study is halted; data from all patients are used in the analysis, including data from patients who dropped out, regardless of the duration of follow-up. This article discusses basic concepts in survival analysis, explains technical terms such as censoring, and provides reasons why ordinary methods of analysis cannot be applied to such data. The Kaplan-Meier survival curve is described, as is the Cox proportional hazards regression and the hazard ratio. Supplementary information includes a data file, graphs with explanations, and additional discussions; these are provided to enhance the reader's experience and understanding.

摘要

生存分析用于分析不同时间段随访患者的数据,在研究结束时,感兴趣的二分类事件结局可能已经发生,也可能尚未发生;分析中使用了所有患者的数据,包括失访患者的数据,无论随访时间长短。本文讨论了生存分析的基本概念,解释了诸如删失等技术术语,并说明了普通分析方法不能应用于此类数据的原因。文中描述了Kaplan-Meier生存曲线以及Cox比例风险回归和风险比。补充信息包括一个数据文件、带解释的图表以及额外的讨论;提供这些是为了增强读者的体验和理解。

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Survival Analysis, Kaplan-Meier Curves, and Cox Regression: Basic Concepts.生存分析、Kaplan-Meier曲线和Cox回归:基本概念
Indian J Psychol Med. 2023 Jul;45(4):434-435. doi: 10.1177/02537176231176986. Epub 2023 Jun 11.
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