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1
Hematuria and dietary supplements - A case report on pronounced bleeding following a minimally invasive urological intervention in a patient on long term garlic supplements.血尿与膳食补充剂——一例长期服用大蒜补充剂的患者在微创泌尿外科手术后出现明显出血的病例报告
Urol Case Rep. 2023 Jul 4;50:102493. doi: 10.1016/j.eucr.2023.102493. eCollection 2023 Sep.
2
Allicin Bioavailability and Bioequivalence from Garlic Supplements and Garlic Foods.大蒜补充剂和大蒜食品中的蒜素生物利用度和生物等效性。
Nutrients. 2018 Jun 24;10(7):812. doi: 10.3390/nu10070812.
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Supplementation of garlic and coriander seed powder: Impact on body mass index, lipid profile and blood pressure of hyperlipidemic patients.大蒜和芫荽籽粉补充剂:对高脂血症患者体重指数、血脂谱和血压的影响。
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Hypocholesterolemic effect of an enteric-coated garlic supplement.一种肠溶包衣大蒜补充剂的降胆固醇作用。
J Am Coll Nutr. 2001 Jun;20(3):225-31. doi: 10.1080/07315724.2001.10719036.
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Low allicin release from garlic supplements: a major problem due to the sensitivities of alliinase activity.大蒜补充剂中蒜素释放量低:由于蒜氨酸酶活性的敏感性而导致的一个主要问题。
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J Nutr. 2001 Mar;131(3s):955S-62S. doi: 10.1093/jn/131.3.955S.
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Short-term garlic supplementation and highly active antiretroviral treatment adherence, CD4+ cell counts, and human immunodeficiency virus viral load.短期补充大蒜与高效抗逆转录病毒治疗依从性、CD4 + 细胞计数及人类免疫缺陷病毒病毒载量的关系
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Nutraceutical use of garlic sulfur-containing compounds.大蒜含硫化合物的营养药用。
Adv Exp Med Biol. 2010;698:110-21. doi: 10.1007/978-1-4419-7347-4_9.
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Dietary supplements and bleeding.膳食补充剂与出血
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Bleeding risk of dietary supplements: A hidden nightmare for cardiac surgeons.膳食补充剂的出血风险:心脏外科医生的潜在噩梦。
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Photoselective vaporization with the green light laser vs transurethral resection of the prostate for treating benign prostate hyperplasia: a systematic review and meta-analysis.绿光激光前列腺选择性光汽化术与经尿道前列腺电切术治疗良性前列腺增生症的系统评价和荟萃分析。
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Garlic compounds generate reactive oxygen species leading to activation of stress kinases and cysteine proteases for apoptosis in human glioblastoma T98G and U87MG cells.大蒜化合物产生活性氧,导致应激激酶和半胱氨酸蛋白酶激活,从而使人胶质母细胞瘤T98G和U87MG细胞发生凋亡。
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Trends in access to complementary or alternative medicines via primary care in England: 1995-2001 results from a follow-up national survey.1995 - 2001年英国通过初级医疗保健获取补充或替代药物的趋势:一项全国性跟踪调查结果
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血尿与膳食补充剂——一例长期服用大蒜补充剂的患者在微创泌尿外科手术后出现明显出血的病例报告

Hematuria and dietary supplements - A case report on pronounced bleeding following a minimally invasive urological intervention in a patient on long term garlic supplements.

作者信息

Nair Arun, Abdelqader Bushra, Sureshkumar Seetha, Katmawai-Sabbagh Samer

机构信息

Department of Urology, St Georges University Hospital, Blackshaw Road, London, SW17 0QT, UK.

Department of Haematology, St Georges University Hospital, Blackshaw Road, London, SW17 0QT, UK.

出版信息

Urol Case Rep. 2023 Jul 4;50:102493. doi: 10.1016/j.eucr.2023.102493. eCollection 2023 Sep.

DOI:10.1016/j.eucr.2023.102493
PMID:37484191
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10362071/
Abstract

This report focuses on a patient encounter with suspected significant hematuria post operation occurring primarily due to garlic supplementation. A 65-year-old male underwent day case PVP. He had significant hematuria post operation requiring added use of bipolar coagulation. He was fit and well with no other past medical or drug history apart from dietary supplementation of garlic extracts. There are various mechanisms that components of garlic like allicin can produce antiplatelet effect on blood. This represents a novel case of unexpected bleeding in patient strongly attributed to dietary supplements for a less invasive technique with better hemostatic profile like PVP.

摘要

本报告重点关注一例术后疑似严重血尿的患者病例,主要原因是补充大蒜。一名65岁男性接受了日间经皮前列腺汽化电切术(PVP)。术后出现严重血尿,需要额外使用双极电凝。除了饮食中补充大蒜提取物外,他身体健康,无其他既往病史或用药史。大蒜中的成分如大蒜素可通过多种机制对血液产生抗血小板作用。这是一例因饮食补充剂导致意外出血的新病例,该患者接受的是侵入性较小且止血效果较好的技术,如PVP。