Thangavel Shifan, Korsholm Kasper, Veien Karsten Tange, Larsen Kim M, Andersen Asger
Department of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200, Aarhus N, Denmark.
Prehospital Emergency Medical Services, Central Denmark Region, Aarhus N, Denmark.
Eur Heart J Case Rep. 2023 Jul 12;7(7):ytad307. doi: 10.1093/ehjcr/ytad307. eCollection 2023 Jul.
Pulmonary embolism (PE) is common, and it is the third leading cause of cardiovascular death. The management of patients with high-risk PE generally consists of systemic thrombolysis; however, surgical or catheter-directed treatment (CDT) can be considered in selected cases.
A 78-year-old female patient presenting with acute severe dyspnoea develops out-of-hospital cardiac arrest (OHCA). She was admitted with return of spontaneous circulation and a critical haemodynamic state upon arrival to the catheterization laboratory with an estimated no-flow time of 1 min and low-flow time of 52 min. An acute pulmonary angiogram reveals massive PE. After a PE response team conference, the patient was not found eligible for extracorporeal membrane oxygenation, surgery, or thrombolysis. The patient was treated with catheter-directed mechanical thrombectomy 129 min after first medical contact. The patient recovered and was discharged without any neurological deficits.
Catheter-directed mechanical thrombectomy was a successful treatment in a patient with OHCA secondary to high-risk PE, where thrombolysis and surgical interventions were considered contraindicated. This case underlines the future perspectives of CDT and also that a multidisciplinary team approach may benefit patients with high-risk PE.
肺栓塞(PE)很常见,是心血管死亡的第三大原因。高危PE患者的治疗通常包括全身溶栓;然而,在某些特定情况下可考虑手术或导管定向治疗(CDT)。
一名78岁女性患者,因急性严重呼吸困难发生院外心脏骤停(OHCA)。她在恢复自主循环后入院,到达导管室时处于危急血流动力学状态,估计无血流时间为1分钟,低血流时间为52分钟。急性肺血管造影显示大面积PE。经过PE反应小组会诊,该患者不符合体外膜肺氧合、手术或溶栓的条件。在首次医疗接触后129分钟,该患者接受了导管定向机械血栓切除术治疗。患者康复出院,无任何神经功能缺损。
导管定向机械血栓切除术是治疗因高危PE继发OHCA患者的一种成功方法,在该病例中溶栓和手术干预被视为禁忌。该病例强调了CDT的未来前景,也表明多学科团队方法可能使高危PE患者受益。