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50g 口服葡萄糖耐量试验对健康妊娠胎儿腹腔动脉和肠系膜上动脉多普勒参数的影响。

The effect of 50 GR oral glucose tolerance test on fetal celiac artery and superior mesenteric artery Doppler parameters in healthy pregnancies.

机构信息

Division of Perinatology, Department of Obstetrics and Gynecology, Faculty of Medicine, Selcuk University, Konya, Türkiye.

Division of Gynecological Oncology, Department of Obstetrics and Gynecology, Faculty of Medicine, Selcuk University, Konya, Türkiye.

出版信息

J Perinat Med. 2023 Jul 25;51(9):1220-1224. doi: 10.1515/jpm-2023-0168. Print 2023 Nov 27.

DOI:10.1515/jpm-2023-0168
PMID:37485973
Abstract

OBJECTIVES

To understand the effect of 50-g oral glucose tolerance test (OGTT) on fetal celiac artery and superior mesenteric artery (SMA) Doppler parameters.

METHODS

A total of 43 healthy pregnant women followed in our hospital were included in the study. All Doppler parameters of the celiac artery and SMA (peak systolic velocity (PSV); pulsatility index (PI); resistance index (RI); systolic/diastolic ratio (SD); time average maximum velocity (TAMAX)) were obtained by ultrasonography before and 1 h after OGTT.

RESULTS

The mean PSV value of the celiac artery decreased statistically significantly after OGTT (37.29 ± 11.96 cm/s; 29.51 ± 10.07 cm/s; p=0.002). While the mean of the PI was 2.09 ± 0.57 before the test, it was found to be 1.84 ± 0.64 after the test (p=0.027). Mean PSV (39.82 ± 13.07 cm/s; 35.19 ± 15.27 cm/s; p=0.104) and PI (2.21 ± 0.65; 2.11 ± 0.80; p=0.375) values of SMA were also found to be decreased without statistically significancy.

CONCLUSIONS

The data obtained from our study reveals that the PSV and PI values of celiac artery and SMA slightly decrease after OGTT.

摘要

目的

了解 50g 口服葡萄糖耐量试验(OGTT)对胎儿腹腔动脉和肠系膜上动脉(SMA)多普勒参数的影响。

方法

本研究共纳入 43 例在我院就诊的健康孕妇。所有孕妇均行超声检查获取腹腔动脉和 SMA 的多普勒参数,包括峰值收缩速度(PSV);搏动指数(PI);阻力指数(RI);收缩期/舒张期比值(SD);时间平均最大速度(TAMAX)。OGTT 前和 1h 后分别测量上述参数。

结果

OGTT 后,腹腔动脉 PSV 均值显著降低(37.29±11.96cm/s;29.51±10.07cm/s;p=0.002)。试验前,PI 均值为 2.09±0.57,试验后为 1.84±0.64(p=0.027)。SMA 的 PSV(39.82±13.07cm/s;35.19±15.27cm/s;p=0.104)和 PI(2.21±0.65;2.11±0.80;p=0.375)均值也略有降低,但无统计学意义。

结论

本研究表明,OGTT 后,胎儿腹腔动脉和 SMA 的 PSV 和 PI 值略有降低。

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