Department of Surgery, Parkland Health and Hospital System, Dallas, TX, USA.
Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA.
J Burn Care Res. 2023 Sep 7;44(5):1253-1257. doi: 10.1093/jbcr/irad111.
Burn patients are particularly susceptible to atypical and opportunistic infections. Here we report an unusual case of a 40-year-old previously healthy man with a 74% TBSA burn injury who developed a presumed Fusarium brain abscess. This patient had a complicated infectious course including ESBL E. coli and Elizabethkingia bacteremia and pneumonia, MRSA ventilator-associated pneumonia, Mycobacterium abscessus bacteremia, and Fusarium fungemia. After diagnosis with a fungal abscess on magnetic resonance imaging of the brain, the patient was treated with aspiration and appropriate antifungal therapies. The patient was eventually transitioned to comfort care and died on hospital day 167. This is the first published report of a Fusarium-related brain abscess since it was first reported in a case report of a burned child in 1974.
烧伤患者特别容易受到非典型和机会性感染。在这里，我们报告了一例不常见的病例，一名 40 岁的既往健康男性，烧伤面积为 74%TBSA，发生了疑似镰刀菌脑脓肿。该患者感染过程复杂，包括产超广谱β-内酰胺酶大肠杆菌和伊丽莎白菌血症和肺炎、耐甲氧西林金黄色葡萄球菌呼吸机相关性肺炎、脓肿分枝杆菌菌血症和镰刀菌菌血症。在脑磁共振成像诊断为真菌性脓肿后，患者接受了抽吸和适当的抗真菌治疗。患者最终转入舒适护理，并于入院第 167 天死亡。这是自 1974 年首例烧伤儿童病例报告以来首次发表的镰刀菌相关脑脓肿报告。
