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涎腺镜治疗涎腺疾病:已发表系统评价和荟萃分析的综合分析。

Sialendoscopy for treatment of major salivary glands diseases: a comprehensive analysis of published systematic reviews and meta-analyses.

机构信息

Faculdade Israelita de Ciências da Saúde Albert Einstein, Serviço de Cirurgia de Cabeça e Pescoço, São Paulo, SP, Brazil.

Universidade de Pernambuco (UPE), Pernambuco, PE, Brazil; Vice-presidente da Sociedade Brasileira de Cirurgia de Cabeça e Pescoço, Brazil.

出版信息

Braz J Otorhinolaryngol. 2023 Sep-Oct;89(5):101293. doi: 10.1016/j.bjorl.2023.101293. Epub 2023 Jul 15.

DOI:10.1016/j.bjorl.2023.101293
PMID:37487402
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10382863/
Abstract

OBJECTIVES

Sialendoscopy is a minimally invasive procedure used to diagnose and treat obstructive salivary gland diseases. Previous studies in the topic have shown mixed results. The present study aimed to evaluate the efficacy and safety of sialendoscopy through previous systematic reviews for different outcomes of several diseases. We also aimed to assess studies' methodological quality and heterogeneity.

METHODS

We conducted a comprehensive systematic literature search of Pubmed, Embase, Lilacs and Cochrane Library. We included systematic reviews and meta-analyses that used sialendoscopy to treat both lithiasic and alithiasic salivary glands diseases. Data extraction included studies' characteristics and results. We assessed studies' methodological quality using the AMSTAR-2 (A MeaSurement Tool to Assess systematic Reviews 2) tool.

RESULTS

13 studies were included in the review, being 9 in adult populations and 4 in pediatric populations. Sialendoscopy proved to be effective at the treatment of different lithiasic and other obstructive diseases, but with important heterogeneity. The technique was also considered highly safe in most studies. However, studies had a critically low quality of evidence.

CONCLUSIONS

Most studies demonstrated high efficacy and safety of sialendoscopy, but with critically low quality of evidence. We still lack randomized studies in this field, and future systematic reviews on the topic should follow current guidelines to improve conduction and reporting.

摘要

目的

涎腺内镜是一种用于诊断和治疗涎腺阻塞性疾病的微创方法。之前在该主题上的研究结果喜忧参半。本研究旨在通过之前的系统评价评估涎腺内镜在治疗多种疾病的不同结局方面的疗效和安全性。我们还旨在评估研究的方法学质量和异质性。

方法

我们对 Pubmed、Embase、Lilacs 和 Cochrane Library 进行了全面的系统文献检索。我们纳入了使用涎腺内镜治疗结石性和非结石性涎腺疾病的系统评价和荟萃分析。数据提取包括研究的特征和结果。我们使用 AMSTAR-2(评估系统评价的测量工具 2)工具评估研究的方法学质量。

结果

共纳入 13 项研究,其中 9 项为成人人群研究,4 项为儿科人群研究。涎腺内镜在治疗不同的结石性和其他阻塞性疾病方面被证明是有效的,但存在重要的异质性。在大多数研究中,该技术也被认为是高度安全的。然而,研究的证据质量极低。

结论

大多数研究表明涎腺内镜具有高疗效和安全性,但证据质量极低。在该领域,我们仍然缺乏随机研究,未来关于该主题的系统评价应遵循当前指南,以提高研究的进行和报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/067f/10382863/d5e563e06485/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/067f/10382863/d5e563e06485/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/067f/10382863/d5e563e06485/gr1.jpg

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