Department of Dermatology, Soroka University Medical Center, Beer-Sheva, Israel.
Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Am J Trop Med Hyg. 2023 Jul 24;109(3):624-625. doi: 10.4269/ajtmh.23-0177. Print 2023 Sep 6.
Cutaneous leishmaniasis (CL) is a skin infection caused by various species of the Leishmania parasite and is spread by the bite of an infected female sandfly. In southern Israel, CL caused by Leishmania major is endemic. Cutaneous leishmaniasis is considered a self-limiting disease, characterized by progressive, long-lasting nodulo-ulcerative skin lesions, which usually resolve in several months to years, and leads to scarring, cosmetic disfigurement, and future stigmatization. Although CL is a common disease among children, reports of CL in children younger than 1 year are rare. We present a case of extensive facial CL in an infant whose initial lesions appeared only 25 days after birth. The patient was treated with intravenous liposomal amphotericin B. Two months later, marked improvement was seen, with complete resolution of the inflammation and atrophic scar formation. To our knowledge, this is the earliest age of CL published to date.
皮肤利什曼病（cutaneous leishmaniasis，CL）是一种由利什曼原虫的各种物种引起的皮肤感染，通过受感染的雌性沙蝇叮咬传播。在以色列南部，由利什曼原虫引起的皮肤利什曼病是地方性的。皮肤利什曼病被认为是一种自限性疾病，其特征为进行性、持久的结节溃疡性皮肤损伤，通常在数月至数年内消退，并导致瘢痕、美容缺陷和未来的污名化。尽管 CL 是儿童中的常见病，但报告的 1 岁以下儿童 CL 病例很少见。我们报告了一例婴儿广泛的面部 CL，其最初的病变仅在出生后 25 天出现。该患者接受了静脉注射脂质体两性霉素 B 治疗。两个月后，炎症明显改善，完全消退，形成萎缩性瘢痕。据我们所知，这是迄今为止报道的最早的 CL 发病年龄。
