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计算机断层扫描肺动脉造影在维多利亚州某地区急诊科的应用

The Utilisation of Computed Tomography Pulmonary Angiography in a Regional Victorian Emergency Department.

作者信息

Uthuman Ali, Kim Tae H, Sountharalingam Subatharshini

机构信息

Rural Health, University of Melbourne, Shepparton, AUS.

General Medicine, Goulburn Valley Health, Shepparton, AUS.

出版信息

Cureus. 2023 Jun 22;15(6):e40833. doi: 10.7759/cureus.40833. eCollection 2023 Jun.

Abstract

BACKGROUND

Pulmonary embolism (PE) is a critical condition with various recognized risk factors. This study investigates these factors in a regional Australian population.

AIMS

The primary aim is to examine the significance of traditional risk factors in the clinical decision to request a computed tomography pulmonary angiography (CTPA) scan for suspected PE within this population and assess the association between the timing of CTPA requests (office vs. after-hours) and PE occurrence.

METHODS

In this single-center retrospective study, we analyzed data from 434 patients undergoing CTPA at Goulburn Valley Health's (GVH) emergency department (ED) between January and August 2022. Covariates included age, clinical indications, and medical background. Statistical tests were applied with a p-value <0.05 indicating significance.

RESULTS

Pulmonary embolism was diagnosed in 39 (20.9%) males and 17 (6.9%) females, with a mean age of 65.04 years (SD: 16.11). Univariate regression indicated a positive association between age and PE. Multivariate analysis showed a significant positive association for unilateral lower limb (LL) swelling/deep vein thrombosis (DVT) (OR: 5.474, p=0.003) and a significant negative association for being female (OR: 0.308, p<0.001). Variables such as shortness of breath, tachycardia, syncope, and chest pain were not significantly associated with PE. No association was found between CTPA request time and PE (χ²=0.9535, df=1, p=0.3288).

CONCLUSION

Increasing age and unilateral LL swelling/DVT are significantly associated with PE. Some signs and symptoms showed negative or positive odds but were not statistically significant. The timing of CTPA requests did not correlate with PE incidence.

摘要

背景

肺栓塞(PE)是一种危急病症,存在多种已被确认的风险因素。本研究对澳大利亚某地区人群中的这些因素进行调查。

目的

主要目的是检验传统风险因素在该人群中针对疑似肺栓塞患者进行计算机断层扫描肺动脉造影(CTPA)扫描的临床决策中的重要性,并评估CTPA检查申请时间(上班时间与非上班时间)与肺栓塞发生之间的关联。

方法

在这项单中心回顾性研究中,我们分析了2022年1月至8月期间在古尔本谷健康中心(GVH)急诊科接受CTPA检查的434例患者的数据。协变量包括年龄、临床指征和病史。采用统计学检验,p值<0.05表示具有显著性。

结果

39名男性(20.9%)和17名女性(6.9%)被诊断为肺栓塞,平均年龄为65.04岁(标准差:16.11)。单因素回归显示年龄与肺栓塞呈正相关。多因素分析显示单侧下肢(LL)肿胀/深静脉血栓形成(DVT)呈显著正相关(比值比:5.474,p = 0.003),女性呈显著负相关(比值比:0.308,p < 0.001)。呼吸急促、心动过速、晕厥和胸痛等变量与肺栓塞无显著关联。CTPA检查申请时间与肺栓塞之间未发现关联(χ² = 0.9535,自由度 = 1,p = 0.3288)。

结论

年龄增加和单侧LL肿胀/DVT与肺栓塞显著相关。一些体征和症状显示出阴性或阳性比值,但无统计学显著性。CTPA检查申请时间与肺栓塞发生率无关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51c7/10363258/23ac449c1ded/cureus-0015-00000040833-i01.jpg

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