血清长链非编码 RNA 对射频消融后持续性心房颤动复发的预测价值。

Predictive value of serum lncRNA for the recurrence of persistent atrial fibrillation after radiofrequency ablation.

机构信息

Department of Cardiology, People's Hospital of Qianxinan Buyi & Miao Minority Autonomous Prefecture, Guizhou Province, China.

Department of Cardiology, Affiliated Hospital of Guizhou Medical University, No. 29 Guiyi Street, Beijing Road, Yunyan District, Guiyang City, Guizhou Province, China.

出版信息

Biomark Med. 2023 Apr;17(8):417-426. doi: 10.2217/bmm-2022-0697. Epub 2023 Jul 25.

DOI:10.2217/bmm-2022-0697

PMID:37489941

Abstract

The authors investigated the predictive value of for persistent atrial fibrillation (PAF) recurrence after radiofrequency ablation. Serum level was determined. The correlation between and high-sensitivity C-reactive protein/left atrial diameter (LAD) was analyzed. The predictive value of MALAT1 was evaluated. The postoperative recurrence rate in patients with high/low was compared. Independent risk factors for postoperative recurrence were analyzed. was elevated in PAF patients and positively correlated with high-sensitivity C-reactive protein/LAD. /high-sensitivity C-reactive protein/LAD were enhanced in patients with recurrent PAF. Patients with high had a higher recurrence rate. Upregulated was an independent risk factor for postoperative PAF recurrence. Serum level >2.03 predicts postoperative recurrence of PAF, and PAF patients with high have a higher risk of postoperative recurrence.

摘要

作者研究了对于射频消融后持续性心房颤动（PAF）复发的预测价值。测定了血清水平。分析了与高敏 C 反应蛋白/左心房直径（LAD）之间的相关性。评估了 MALAT1 的预测价值。比较了高/低患者术后复发率。分析了术后复发的独立危险因素。PAF 患者的升高，与高敏 C 反应蛋白/LAD 呈正相关。复发性 PAF 患者的 /高敏 C 反应蛋白/LAD 增强。高的患者复发率更高。上调的是术后 PAF 复发的独立危险因素。血清水平>2.03 预测 PAF 术后复发，且高的 PAF 患者术后复发风险更高。