[磁共振引导聚焦超声分次及同期双侧丘脑切开术治疗特发性震颤的经验]
[Experience of staged and simultaneous bilateral thalamotomy using MR-guided focused ultrasound in the treatment of essential tremor].
作者信息
Nabiullina D I, Galimova R M, Illarioshkin S N, Buzaev I V, Safin Sh M, Akhmadeeva G N, Mukhamadeeva N R, Krekotin D K
机构信息
Buzaev Clinics of Intellectual Neurosurgery the International Medical Center, Ufa, Russia.
Bashkir State Medical University, Ufa, Russia.
出版信息
Zh Nevrol Psikhiatr Im S S Korsakova. 2023;123(7):65-73. doi: 10.17116/jnevro202312307165.
OBJECTIVE
To show that effective and safe bilateral MR-guided focused ultrasound (MRgFUS) treatment of essential tremor (ET) is achievable.
MATERIAL AND METHODS
Four male patients underwent bilateral thalamotomy. Two patients underwent staged thalamotomy, with the ≥12 month interval between operations. Two patients underwent simultaneous bilateral thalamotomy.
RESULTS
After six months, all patients noted a significant reduction in symptoms on both sides: when assessing tremors with the Clinical Rating Scale for Tremor, the severity of hyperkinesis decreased by 57.5-69.7%. We did not observe any complications in any of the cases.
CONCLUSION
Our experience indicates that simultaneous bilateral MRI-guided focused ultrasound treatment of ET can be performed safely and effectively. Further research is necessary to estimate the effectiveness and adverse effect rates.
目的
证明对特发性震颤（ET）进行有效且安全的双侧磁共振引导聚焦超声（MRgFUS）治疗是可行的。
材料与方法
四名男性患者接受了双侧丘脑切开术。两名患者接受分期丘脑切开术，手术间隔≥12个月。两名患者接受同期双侧丘脑切开术。
结果
六个月后，所有患者均指出两侧症状显著减轻：使用震颤临床评定量表评估震颤时，运动亢进严重程度降低了57.5 - 69.7%。我们在任何病例中均未观察到任何并发症。
结论
我们的经验表明，对ET进行同期双侧磁共振引导聚焦超声治疗可安全有效地进行。有必要进行进一步研究以评估疗效和不良反应发生率。
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