Nabiullina D I, Galimova R M, Illarioshkin S N, Buzaev I V, Safin Sh M, Akhmadeeva G N, Mukhamadeeva N R, Krekotin D K
Buzaev Clinics of Intellectual Neurosurgery the International Medical Center, Ufa, Russia.
Bashkir State Medical University, Ufa, Russia.
Zh Nevrol Psikhiatr Im S S Korsakova. 2023;123(7):65-73. doi: 10.17116/jnevro202312307165.
To show that effective and safe bilateral MR-guided focused ultrasound (MRgFUS) treatment of essential tremor (ET) is achievable.
Four male patients underwent bilateral thalamotomy. Two patients underwent staged thalamotomy, with the ≥12 month interval between operations. Two patients underwent simultaneous bilateral thalamotomy.
After six months, all patients noted a significant reduction in symptoms on both sides: when assessing tremors with the Clinical Rating Scale for Tremor, the severity of hyperkinesis decreased by 57.5-69.7%. We did not observe any complications in any of the cases.
Our experience indicates that simultaneous bilateral MRI-guided focused ultrasound treatment of ET can be performed safely and effectively. Further research is necessary to estimate the effectiveness and adverse effect rates.
证明对特发性震颤（ET）进行有效且安全的双侧磁共振引导聚焦超声（MRgFUS）治疗是可行的。
四名男性患者接受了双侧丘脑切开术。两名患者接受分期丘脑切开术，手术间隔≥12个月。两名患者接受同期双侧丘脑切开术。
六个月后，所有患者均指出两侧症状显著减轻：使用震颤临床评定量表评估震颤时，运动亢进严重程度降低了57.5 - 69.7%。我们在任何病例中均未观察到任何并发症。
我们的经验表明，对ET进行同期双侧磁共振引导聚焦超声治疗可安全有效地进行。有必要进行进一步研究以评估疗效和不良反应发生率。
